{"id":"W2954220199","doi":"10.3390/cancers11070904","title":"Wnt Signaling in Cancer Metabolism and Immunity","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Wnt signaling pathway; Tumor microenvironment; Biology; Cancer research; Cancer stem cell; Glutaminolysis; Carcinogenesis; Cancer; Cancer immunotherapy; LRP6; Cancer cell; Reprogramming; Cell biology; Immune system; Signal transduction; Immunotherapy; Immunology; Stem cell; Cell; Tumor cells; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002287587,0.0006453205,0.0006812614,0.001550255,0.0002673961,0.0007746122,0.0004329312,0.0007281216,0.004647375],"category_scores_gemma":[0.0003254516,0.0001742148,0.0002754535,0.001687607,0.0003131384,0.0008722816,0.0005888708,0.001222672,0.002698565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006210122,"about_ca_system_score_gemma":0.0009166005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000948053,"about_ca_topic_score_gemma":0.001845935,"domain_scores_codex":[0.9999143,0.00001280891,0.00001144447,0.00001485483,0.00003425363,0.00001232766],"domain_scores_gemma":[0.9999002,0.00003668652,0.00001459796,0.000003844852,0.00002939569,0.00001519529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004942918,0.00003618038,0.0001502465,0.007993884,0.00003906879,0.0002295095,0.00006626863,0.0003818315,0.003917534,0.007378773,0.03111273,0.9486446],"study_design_scores_gemma":[0.000003847355,0.00002913589,0.0003829327,0.001044346,0.00002429681,0.0007074173,0.00003009745,0.00004524583,0.0003540476,0.001836133,0.9955351,0.000007281437],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001599489,0.996708,0.0001721608,0.0002986304,0.0002720684,0.000003682746,0.00002331344,0.00001182658,0.002350321],"genre_scores_gemma":[0.0008606464,0.9972327,0.0001586315,0.0001426813,0.0001401514,0.000003862452,0.00003353902,0.000001646697,0.001426133],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004647375,"threshold_uncertainty_score":0.01554704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05493174862679723,"score_gpt":0.3582776268211471,"score_spread":0.3033458781943498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}