{"id":"W2954220199","doi":"10.3390/cancers11070904","title":"Wnt Signaling in Cancer Metabolism and Immunity","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Wnt signaling pathway; Tumor microenvironment; Biology; Cancer research; Cancer stem cell; Glutaminolysis; Carcinogenesis; Cancer; Cancer immunotherapy; LRP6; Cancer cell; Reprogramming; Cell biology; Immune system; Signal transduction; Immunotherapy; Immunology; Stem cell; Cell; Tumor cells; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001789748,0.0002062029,0.0005525519,0.00006805718,0.00002772485,0.00001767801,0.0001279888,0.0002720018,0.00001801131],"category_scores_gemma":[0.00002505725,0.0001856549,0.0001191507,0.0001007343,0.00003702856,0.000001578923,0.00008043462,0.0001765455,0.000003106233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001656774,"about_ca_system_score_gemma":0.0007374384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005183412,"about_ca_topic_score_gemma":0.0001576502,"domain_scores_codex":[0.9990953,0.0000977886,0.0002472749,0.0003147162,0.00006753325,0.0001773936],"domain_scores_gemma":[0.9995241,0.00001664637,0.000145624,0.000235771,0.00002979087,0.00004808493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006272834,0.000004015713,0.00003053316,0.002857858,0.00009947534,0.000001000153,0.00003502623,0.0002940338,0.002712942,0.00002109951,0.00004364733,0.9938941],"study_design_scores_gemma":[0.0001421429,0.00002233784,0.00001934721,0.001047095,0.0001562563,5.715648e-7,0.00001001282,0.00000619707,0.0012719,0.00001717394,0.9970741,0.0002329253],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004948005,0.9940647,0.00001642445,0.000003468565,0.0003422463,0.0002986422,0.0000382133,0.000002967593,0.0002853108],"genre_scores_gemma":[0.001332012,0.997838,0.00005669516,0.00002501305,0.0002221797,0.00008461858,0.0001242523,0.00003296294,0.0002842265],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9970304,"threshold_uncertainty_score":0.7570788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05493174862679723,"score_gpt":0.3582776268211471,"score_spread":0.3033458781943498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}