{"id":"W2954280934","doi":"10.1053/j.gastro.2019.05.072","title":"Challenges in the Pathophysiology, Diagnosis, and Management of Intestinal Fibrosis in Inflammatory Bowel Disease","year":2019,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Cancer Center Amsterdam; Universiteit Utrecht; Union Chimique Belge; Celgene; National Institute of Diabetes and Digestive and Kidney Diseases; Gilead Sciences; GlaxoSmithKline; Pfizer","keywords":"Medicine; Fibrosis; Inflammatory bowel disease; Crohn's disease; Extracellular matrix; Pathophysiology; Clinical trial; Disease; Pathology; Immunology; Bioinformatics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002454387,0.000137093,0.0001293561,0.00007042012,0.00001191598,0.000004678054,0.0002256684,0.00006044003,0.000009218337],"category_scores_gemma":[0.00001864553,0.0001156619,0.00004859302,0.00002516947,0.0001292977,0.000005074978,0.0002009491,0.00009015422,0.000005811469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008882796,"about_ca_system_score_gemma":0.00001255956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003243494,"about_ca_topic_score_gemma":0.000130588,"domain_scores_codex":[0.9988487,0.0002463097,0.0002367878,0.0003305862,0.00007220919,0.0002653685],"domain_scores_gemma":[0.999463,0.00001745261,0.00007686415,0.0003728874,0.00001710802,0.0000526907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001091453,0.0001307676,0.9947195,0.0002903001,0.00002003176,0.0001470751,0.00008037063,0.00009268105,0.002511255,0.0002948486,0.00005955242,0.0005621821],"study_design_scores_gemma":[0.001027532,0.0002922115,0.9978372,0.00007706345,0.00001225727,0.000006056669,0.0002369963,0.00003560944,0.00006714933,0.0001845895,0.0001584271,0.0000648613],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982796,0.0007146026,0.000004334874,0.000416826,0.00005834656,0.0003859395,0.00001071113,0.000003743848,0.0001258402],"genre_scores_gemma":[0.9968203,0.002477303,0.0000882141,0.0003445093,0.00002654982,0.0002007269,0.00002498384,0.00001061974,0.000006846872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003117763,"threshold_uncertainty_score":0.4716553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0103208368927479,"score_gpt":0.2276723388207662,"score_spread":0.2173515019280182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}