{"id":"W2954307091","doi":"10.1016/j.stem.2019.06.010","title":"Defining Human Pluripotency","year":2019,"lang":"en","type":"review","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Hebrew University of Jerusalem; United States-Israel Binational Science Foundation","keywords":"Induced pluripotent stem cell; Biology; Embryonic stem cell; Cell potency; Germ layer; Cell biology; Somatic cell; Regenerative medicine; Stem cell; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001434024,0.001568366,0.001201182,0.001816335,0.0003849879,0.001413704,0.001070055,0.001467363,0.002413951],"category_scores_gemma":[0.0009445988,0.0004478658,0.0003253707,0.00171397,0.001997219,0.002044334,0.001664273,0.003082527,0.002364678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001525453,"about_ca_system_score_gemma":0.00140288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001319925,"about_ca_topic_score_gemma":0.002054935,"domain_scores_codex":[0.9997024,0.00006762736,0.00003701111,0.00006298372,0.00009328901,0.00003660165],"domain_scores_gemma":[0.9997265,0.0001370428,0.00002683106,0.0000157208,0.00006477546,0.00002908615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007188033,0.00003266616,0.0001413516,0.007336414,0.00003285352,0.0002388858,0.0000865325,0.0004363858,0.0044184,0.03756693,0.07269602,0.8769417],"study_design_scores_gemma":[0.000008668484,0.00001858887,0.0001222691,0.0007266409,0.00001742287,0.0002898181,0.00002447749,0.00004308168,0.0007633332,0.00568949,0.9922884,0.000007643048],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009776657,0.9931074,0.000855929,0.000883065,0.001339092,0.000007563592,0.00002842533,0.00001312021,0.003667703],"genre_scores_gemma":[0.001238939,0.9917021,0.000798334,0.001776425,0.0009877901,0.00002241277,0.00008470205,0.000007490468,0.003381647],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002413951,"threshold_uncertainty_score":0.01106793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03638941056749826,"score_gpt":0.3123989997175402,"score_spread":0.2760095891500419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}