{"id":"W2954307091","doi":"10.1016/j.stem.2019.06.010","title":"Defining Human Pluripotency","year":2019,"lang":"en","type":"review","venue":"Cell stem cell","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Hebrew University of Jerusalem; United States-Israel Binational Science Foundation","keywords":"Induced pluripotent stem cell; Biology; Embryonic stem cell; Cell potency; Germ layer; Cell biology; Somatic cell; Regenerative medicine; Stem cell; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000469861,0.000852218,0.001555451,0.0002283192,0.0002024213,0.000109531,0.001340845,0.001076379,0.0001724616],"category_scores_gemma":[0.000006945386,0.0007721246,0.001021265,0.0002668911,0.00009355856,0.000004902038,0.0008760556,0.0007055926,0.00451983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001037817,"about_ca_system_score_gemma":0.0005501434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001415849,"about_ca_topic_score_gemma":0.000004520034,"domain_scores_codex":[0.9958336,0.0003807288,0.0008768552,0.001431349,0.0004973607,0.0009801543],"domain_scores_gemma":[0.9973247,0.0000603505,0.0005317921,0.001690573,0.0001075508,0.0002850191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002571587,0.0005853028,0.00002906812,0.1407759,0.0003971542,0.0001809316,0.00006377585,0.00002196501,0.0199078,0.0001052476,0.04631411,0.791593],"study_design_scores_gemma":[0.0003660683,0.0002484372,6.312094e-7,0.001482783,0.0003175493,0.00002733479,0.00001884858,0.000001896491,0.004742663,0.000003129177,0.9919619,0.0008287413],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001126644,0.8969613,0.000032787,0.000002701774,0.0004422585,0.001095809,0.00009336758,0.00003627658,0.1012228],"genre_scores_gemma":[0.0002305806,0.8856203,0.00008877218,0.00002723751,0.000308505,0.0001055014,0.001328431,0.0002292366,0.1120615],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9456478,"threshold_uncertainty_score":0.999473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03638941056749826,"score_gpt":0.3123989997175402,"score_spread":0.2760095891500419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}