{"id":"W2954329183","doi":"10.1186/s12943-019-1043-x","title":"Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA","year":2019,"lang":"en","type":"review","venue":"Molecular Cancer","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":379,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Science and Technology Major Project; McMaster University","keywords":"Liquid biopsy; Hepatocellular carcinoma; Circulating tumor cell; Biopsy; Liver biopsy; Metastasis; Circulating tumor DNA; Pathology; Medicine; Carcinoma; Cancer; Oncology; Internal medicine; Cancer research","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007537603,0.0008407648,0.001368361,0.002997582,0.0002661052,0.001002732,0.0008625527,0.001230097,0.002753051],"category_scores_gemma":[0.001118346,0.0002797588,0.0005990173,0.002403912,0.0006406973,0.001507161,0.0006803306,0.001803505,0.001978278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006838128,"about_ca_system_score_gemma":0.001018525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001115686,"about_ca_topic_score_gemma":0.001778838,"domain_scores_codex":[0.9997374,0.0000550193,0.00003654159,0.00004679449,0.0001014412,0.00002271482],"domain_scores_gemma":[0.9994419,0.0003167462,0.00005465959,0.00001667914,0.0001355683,0.0000343175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006422987,0.00004410705,0.0002829162,0.01331043,0.00006858412,0.0002667515,0.00005276054,0.0002576455,0.001384434,0.002506546,0.02659828,0.9551633],"study_design_scores_gemma":[0.00001219607,0.00008434638,0.0009884113,0.003600765,0.0001005214,0.002403392,0.00005334942,0.0001162864,0.0006748945,0.00171232,0.9902294,0.00002410327],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008447934,0.9984697,0.0001589479,0.0002949504,0.0002631394,0.000003785967,0.00001280738,0.000006992388,0.0007051913],"genre_scores_gemma":[0.0004786018,0.9985384,0.000153553,0.0002078486,0.0001814834,0.000004929035,0.00002786083,0.000001631962,0.000405703],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002997582,"threshold_uncertainty_score":0.009209871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02473386372092003,"score_gpt":0.2785862004330163,"score_spread":0.2538523367120963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}