{"id":"W2954342804","doi":"10.1136/esmoopen-2019-000552","title":"Introducing a new ESMO Open article series: how I treat side effects of immunotherapy","year":2019,"lang":"en","type":"article","venue":"ESMO Open","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Immunotherapy; Oncology; Lung cancer; Internal medicine; Cancer immunotherapy; Clinical trial; Cancer; Melanoma; Pembrolizumab; Cancer research","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003971992,0.0002120424,0.0006071904,0.00007113506,0.0000681545,0.0002163837,0.0007127823,0.00009595243,0.001453743],"category_scores_gemma":[0.00006690223,0.0001696242,0.0001277532,0.0003246818,0.00006781903,0.0006451064,0.0002957171,0.0001460813,0.0001011509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001145287,"about_ca_system_score_gemma":0.0003148305,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01542268,"about_ca_topic_score_gemma":0.0005046518,"domain_scores_codex":[0.998705,0.00008553516,0.0002847383,0.0004079539,0.0002088971,0.0003078563],"domain_scores_gemma":[0.9986487,0.0001162363,0.0001615194,0.0009056925,0.00005813982,0.0001096964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0200226,0.0004833831,0.02306166,0.0003787946,0.001090646,0.00006233046,0.004444058,0.00001251907,0.6385413,0.0003623425,0.031612,0.2799284],"study_design_scores_gemma":[0.02432767,0.002993896,0.1107625,0.001120643,0.0001237755,0.00009480996,0.000687713,0.00004281696,0.7117042,0.0003064822,0.1474031,0.0004323454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9631701,0.0009302401,0.00009343777,0.01048824,0.0005024519,0.00367965,0.000005040782,0.0000448535,0.02108599],"genre_scores_gemma":[0.9205202,0.0005221285,0.003478544,0.002234512,0.0002146423,0.00008486619,0.00002475648,0.00007370315,0.07284666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.279496,"threshold_uncertainty_score":0.9994591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01175579900569069,"score_gpt":0.2828996651209102,"score_spread":0.2711438661152196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}