{"id":"W2954390247","doi":"10.1158/1538-7445.sabcs18-3880","title":"Abstract 3880: In vivo activities of TP-2846: a novel tetracycline antileukemia agent","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fractal Systems (Canada)","funders":"","keywords":"Bioavailability; In vivo; Pharmacokinetics; Pharmacology; Chemistry; Medicine; Biology; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001656446,0.0004620703,0.0003671779,0.0002100825,0.0001069679,0.0001729786,0.0002529761,0.0003569412,0.001921788],"category_scores_gemma":[0.0001923626,0.0001034093,0.0001536185,0.0001323985,0.0001686923,0.0002423017,0.0001208291,0.0006075937,0.0006199027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002535001,"about_ca_system_score_gemma":0.000271293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009810639,"about_ca_topic_score_gemma":0.0009948427,"domain_scores_codex":[0.9999182,0.00002045286,0.000005893693,0.00001520182,0.0000226159,0.00001764324],"domain_scores_gemma":[0.9999032,0.00001749383,0.00002340962,0.00001027527,0.00001434819,0.00003131872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002341349,0.0005603114,0.0003723729,0.0001252882,0.00001676561,0.0001802109,0.00002422225,0.0007340178,0.9787484,0.00007121903,0.0004756857,0.01635014],"study_design_scores_gemma":[0.001127659,0.03651116,0.009245625,0.00002114723,0.00008357993,0.001374711,0.00002345822,0.0037099,0.9365975,0.00008046869,0.01120245,0.00002232145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917518,0.002067699,0.002447138,0.0001647233,0.00004584499,0.0001107622,0.0006650719,0.0001919139,0.002554947],"genre_scores_gemma":[0.9893574,0.001426604,0.002766734,0.00008563235,0.00004508172,0.00009449574,0.001714193,0.00003529849,0.004474512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001921788,"threshold_uncertainty_score":0.006428957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03397247291649929,"score_gpt":0.3622972008661655,"score_spread":0.3283247279496662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}