{"id":"W2954402320","doi":"10.1038/s41598-019-45624-y","title":"Screening of Candida albicans GRACE library revealed a unique pattern of biofilm formation under repression of the essential gene ILS1","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Concordia University","funders":"Fonds de recherche du Québec – Nature et technologies; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biofilm; Mutant; Gene; Biology; Candida albicans; Psychological repression; Yeast; Cell biology; Microbiology; Corpus albicans; Genetics; Gene expression; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001235961,0.0006498339,0.0005292355,0.0004659524,0.0001928237,0.0002623018,0.0002462753,0.0002384589,0.001602814],"category_scores_gemma":[0.000170684,0.0001398594,0.0004214051,0.0003565373,0.0001579535,0.00009173967,0.0003407974,0.000546328,0.0005573707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001685751,"about_ca_system_score_gemma":0.0002792013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001340818,"about_ca_topic_score_gemma":0.001736977,"domain_scores_codex":[0.9997708,0.00001581975,0.00001699178,0.000036686,0.0001126223,0.00004702493],"domain_scores_gemma":[0.9998698,0.00003505637,0.0000185391,0.00001885678,0.00002431748,0.00003328158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004655305,0.00001610189,0.0001752215,0.00001297636,0.000002435263,0.00007025146,0.000008274326,0.00002179834,0.9987986,0.00001852964,0.00003614177,0.0007930671],"study_design_scores_gemma":[0.00001111393,0.0003996137,0.01439442,0.000006360015,0.0000383716,0.0007383638,0.00004948895,0.0007211206,0.9811139,0.00003309625,0.002479994,0.00001418884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894989,0.0004650187,0.004532885,0.0001186217,0.00002583478,0.00007303728,0.003073056,0.0002698958,0.001942928],"genre_scores_gemma":[0.9674366,0.0006934285,0.009145238,0.0001923474,0.00001466461,0.000103486,0.0128208,0.0001425509,0.009450867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001602814,"threshold_uncertainty_score":0.005361974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01151205440277749,"score_gpt":0.2501702778880355,"score_spread":0.238658223485258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}