{"id":"W2954464051","doi":"10.1038/s42003-019-0495-2","title":"Lactate from astrocytes fuels learning-induced mRNA translation in excitatory and inhibitory neurons","year":2019,"lang":"en","type":"article","venue":"Communications Biology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":185,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression; U.S. Department of Health and Human Services","keywords":"Glycogenolysis; Excitatory postsynaptic potential; Inhibitory postsynaptic potential; Gene knockdown; Hippocampus; Neuroscience; Biology; Cell biology; Astrocyte; Glycogen; Chemistry; Biochemistry; Central nervous system; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008921466,0.0002694437,0.0001867648,0.0001041962,0.0001432855,0.0002617589,0.0001168622,0.0001359633,0.0007314051],"category_scores_gemma":[0.00008330501,0.00008007808,0.0001926403,0.00008021045,0.0001665436,0.0002652169,0.0002263949,0.000360197,0.0002844317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002848179,"about_ca_system_score_gemma":0.000289047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009518933,"about_ca_topic_score_gemma":0.001802799,"domain_scores_codex":[0.9999418,0.000006549411,0.000008041713,0.00001210021,0.00001381819,0.00001775897],"domain_scores_gemma":[0.9999433,0.000004815103,0.00001931959,0.000005357976,0.00001169894,0.00001562577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002205115,0.00001224958,0.0001819993,0.00003213701,0.000003378805,0.00003470405,0.0000108426,0.00004214038,0.9982199,0.00008818572,0.00002581065,0.001128256],"study_design_scores_gemma":[0.00001453238,0.0001413131,0.002224328,0.000007312661,0.00001116515,0.00005961125,0.00003006749,0.0004887544,0.9960764,0.0001126199,0.0008315039,0.000002479991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926346,0.001687627,0.003505257,0.0001716575,0.00005459154,0.00001162084,0.0003277217,0.00005783572,0.001549132],"genre_scores_gemma":[0.9947475,0.0007868251,0.00222702,0.00005412836,0.00001209849,0.00001829112,0.0003091263,0.00002621909,0.001818817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009518933,"threshold_uncertainty_score":0.00244683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1139034043317342,"score_gpt":0.3693021764587202,"score_spread":0.255398772126986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}