{"id":"W2954464051","doi":"10.1038/s42003-019-0495-2","title":"Lactate from astrocytes fuels learning-induced mRNA translation in excitatory and inhibitory neurons","year":2019,"lang":"en","type":"article","venue":"Communications Biology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":185,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression; U.S. Department of Health and Human Services","keywords":"Glycogenolysis; Excitatory postsynaptic potential; Inhibitory postsynaptic potential; Gene knockdown; Hippocampus; Neuroscience; Biology; Cell biology; Astrocyte; Glycogen; Chemistry; Biochemistry; Central nervous system; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002213351,0.000121219,0.000171177,0.0002367879,0.000227234,0.000029169,0.0007712274,0.00008995952,0.00005581272],"category_scores_gemma":[0.0003090523,0.0001208538,0.00003047976,0.0003613561,0.0005164099,0.0002151768,0.0003453458,0.0007508195,0.0001683351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001971727,"about_ca_system_score_gemma":0.00006322946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003016211,"about_ca_topic_score_gemma":0.00003011032,"domain_scores_codex":[0.9975581,0.001375697,0.0002317297,0.0004511576,0.00008319662,0.0003001874],"domain_scores_gemma":[0.9970565,0.002136141,0.00007877089,0.000632509,0.00002155107,0.00007450865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003318611,0.00006074143,0.02140578,0.000002740765,0.000001044623,0.000003084562,0.0002446071,0.000005278352,0.9740674,0.0003303187,0.000008278631,0.003837523],"study_design_scores_gemma":[0.002004889,0.0008373138,0.04783392,0.00002278658,0.00001077726,0.00002272075,0.0002178676,0.006244947,0.9243946,0.001136836,0.01690808,0.0003652339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962923,0.0002808342,0.000006165204,0.001430489,0.000191412,0.0003070672,0.00001111094,0.00006249836,0.00141812],"genre_scores_gemma":[0.997779,0.001274477,0.00005876824,0.0007025844,0.00001753145,0.00004091172,0.000005615049,0.00001420886,0.0001069188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04967278,"threshold_uncertainty_score":0.4928277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1139034043317342,"score_gpt":0.3693021764587202,"score_spread":0.255398772126986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}