{"id":"W2954527551","doi":"10.1038/s41598-019-45070-w","title":"Ctt1 catalase activity potentiates antifungal azoles in the emerging opportunistic pathogen Saccharomyces cerevisiae","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Plant-Microbe Interactions and Immunity","field":"Agricultural and Biological Sciences","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University; McGill University Health Centre","funders":"Concordia University; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Antifungal; Saccharomyces cerevisiae; Catalase; Fungal pathogen; Microbiology; Opportunistic pathogen; Pathogen; Biology; Chemistry; Yeast; Biochemistry; Enzyme; Gene; Virulence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008436007,0.0003206374,0.0002752295,0.0001549719,0.00007357387,0.0002996249,0.0001713486,0.0001886118,0.001104308],"category_scores_gemma":[0.0001025148,0.00009721029,0.0001882806,0.0001419405,0.000119061,0.0001080494,0.0001834864,0.0003672115,0.0002650875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000165667,"about_ca_system_score_gemma":0.0001165878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006967308,"about_ca_topic_score_gemma":0.0006212554,"domain_scores_codex":[0.9998959,0.00001714231,0.00001383032,0.00002308019,0.00003361538,0.00001635635],"domain_scores_gemma":[0.9999094,0.00001348679,0.00002489013,0.00001262433,0.00001844847,0.00002114107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005549072,0.00001641206,0.0001799181,0.00002117244,0.000002985895,0.00002626403,0.000003937816,0.00003174592,0.9991629,0.00001132532,0.00002112751,0.0004666571],"study_design_scores_gemma":[0.00001030405,0.0002995853,0.008181581,0.00000778718,0.00001832302,0.0001548771,0.00003631524,0.0007331624,0.9896185,0.00002576367,0.0009094608,0.000004426891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970583,0.0009143449,0.0006250218,0.00008180766,0.00002591474,0.00001135034,0.0004631631,0.0000605134,0.0007596192],"genre_scores_gemma":[0.997559,0.0004477392,0.0005536988,0.00003696177,0.000006893955,0.00001116456,0.0004837126,0.00001313992,0.0008876842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001104308,"threshold_uncertainty_score":0.003694236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01882234667110912,"score_gpt":0.229498767568198,"score_spread":0.2106764208970889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}