{"id":"W2954678167","doi":"10.1002/hed.25868","title":"The role of CIP2A as a therapeutic target of rapamycin in radioresistant head and neck cancer with TP53 mutation","year":2019,"lang":"en","type":"article","venue":"Head & Neck","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"National Research Foundation of Korea","keywords":"Radioresistance; Radiosensitivity; Cancer research; Mutation; Downregulation and upregulation; Senescence; Cancer; Cell culture; Biology; Radiation therapy; Medicine; Cell biology; Genetics; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001661649,0.0003789103,0.00037581,0.0004664646,0.0003175375,0.0003702768,0.000182367,0.0003033032,0.00105638],"category_scores_gemma":[0.000104467,0.000111527,0.0002975868,0.0002348161,0.0003398385,0.0002320304,0.0001512439,0.0004836567,0.0002597963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003933839,"about_ca_system_score_gemma":0.0002772163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005011365,"about_ca_topic_score_gemma":0.0008462894,"domain_scores_codex":[0.9999043,0.00002043524,0.000009101943,0.00001716606,0.0000213217,0.00002775479],"domain_scores_gemma":[0.9999381,0.000008043678,0.00001846601,0.000006724988,0.00001097136,0.00001764275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006510906,0.0001078867,0.001241457,0.0002314216,0.00002310325,0.0002932723,0.00003613786,0.0002109351,0.9909167,0.0002227749,0.0002586895,0.005806534],"study_design_scores_gemma":[0.00007164742,0.001830523,0.01802468,0.00002654139,0.0001136384,0.002362251,0.00008089471,0.001354489,0.9655036,0.0001268188,0.01049098,0.0000140481],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985609,0.01027273,0.001384847,0.0002491373,0.0000515903,0.00007459424,0.0002710506,0.0000963694,0.001990737],"genre_scores_gemma":[0.9952334,0.002239461,0.001243272,0.00004898417,0.00002208509,0.00006333759,0.0003275625,0.0000100518,0.000812032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00105638,"threshold_uncertainty_score":0.0035339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007148077347566496,"score_gpt":0.2587405292604283,"score_spread":0.2515924519128618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}