{"id":"W2954693732","doi":"10.1158/1538-7445.am2019-ct006","title":"Abstract CT006: Clinical study of a personalized neoantigen cancer vaccine in treating patients with advanced malignant tumor","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Cancer; Clinical trial; Cancer vaccine; Immunogenicity; Cancer immunotherapy; Oncology; Peptide vaccine; Immunotherapy; Internal medicine; Immunology; Immune system; Antigen; Epitope","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008836094,0.0004090932,0.001121237,0.000190599,0.0003039232,0.0005134979,0.0002649864,0.000646349,0.004627508],"category_scores_gemma":[0.000755357,0.0001679662,0.0007753748,0.0003054983,0.0003565375,0.0005246341,0.0002693982,0.001505353,0.0007370443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004490498,"about_ca_system_score_gemma":0.001083355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003773238,"about_ca_topic_score_gemma":0.0006046846,"domain_scores_codex":[0.9997808,0.00008158696,0.00002113702,0.00004606069,0.00003124699,0.00003920458],"domain_scores_gemma":[0.9996376,0.00005103462,0.00005462855,0.000031759,0.00005731802,0.0001677123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4902539,0.03933177,0.02856758,0.003758333,0.001549384,0.0005025152,0.000339388,0.00327384,0.06070349,0.001099809,0.01867891,0.351941],"study_design_scores_gemma":[0.2239031,0.6630509,0.05521566,0.0004088295,0.001919976,0.0007431424,0.0001842481,0.004295111,0.01511546,0.0009230199,0.03416859,0.00007176457],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9753416,0.009943043,0.001439793,0.001168218,0.0006062996,0.004261533,0.002604803,0.0001337331,0.004500942],"genre_scores_gemma":[0.9817967,0.002942505,0.001869222,0.001684223,0.0003156492,0.004597754,0.003502502,0.00001992013,0.003271473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004627508,"threshold_uncertainty_score":0.01548052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04709787045956568,"score_gpt":0.4056112250395573,"score_spread":0.3585133545799916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}