{"id":"W2954739480","doi":"10.1016/j.bbi.2019.06.032","title":"Assessing therapeutic response non-invasively in a neonatal rat model of acute inflammatory white matter injury using high-field MRI","year":2019,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Neonatal and fetal brain pathology","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Heart Institute; Université de Montréal; Polytechnique Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Institute of Human Development, Child and Youth Health; Canadian Institutes of Health Research","keywords":"Medicine; Periventricular leukomalacia; White matter; Neuroprotection; Diffusion MRI; Neuroinflammation; Magnetic resonance imaging; Pathology; Inflammation; Anesthesia; Internal medicine; Biology; Radiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000547116,0.0002101404,0.0004462639,0.0002597209,0.00007192328,0.00002555935,0.0001293916,0.0002139316,0.0001015566],"category_scores_gemma":[0.0000311912,0.0001895918,0.00008898476,0.0001663752,0.0001482886,0.0003567235,0.0001814774,0.000518534,0.00001374755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004760594,"about_ca_system_score_gemma":0.0001707068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008621829,"about_ca_topic_score_gemma":0.00000484785,"domain_scores_codex":[0.9986928,0.000221481,0.0003825499,0.0002583558,0.0001673923,0.0002774648],"domain_scores_gemma":[0.9991016,0.0002093727,0.0001250401,0.0004170025,0.00006678211,0.00008024831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001795363,0.00008852597,0.253626,0.00007330418,0.00001888755,0.00008322982,0.001067223,0.000007607959,0.740132,0.00001098752,0.00001905808,0.00307781],"study_design_scores_gemma":[0.002311063,0.0004987511,0.9411982,0.0002333126,0.0001607736,0.0002804747,0.0006022661,0.0008189745,0.05349734,0.0001161504,0.00002211924,0.0002606275],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980787,0.0001097514,0.0005230856,0.0005179305,0.0001280577,0.0005160969,0.00002760676,0.00001808671,0.00008066984],"genre_scores_gemma":[0.9970375,0.00001417711,0.0008894456,0.001445431,0.00001375642,0.00001759929,0.00001925973,0.00002926313,0.00053352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6875722,"threshold_uncertainty_score":0.7731331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02241792449522641,"score_gpt":0.3030629111428021,"score_spread":0.2806449866475758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}