{"id":"W2954889722","doi":"","title":"Pre-clinical safety assessment of VB4-845, an EpCAM binding immunoconjugate","year":2008,"lang":"en","type":"article","venue":"Cancer Research","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Viventia Bio (Canada)","funders":"","keywords":"Antibody; Epitope; Amino acid; Epithelial cell adhesion molecule; Biology; Immunohistochemistry; Recombinant DNA; Molecular biology; Cancer research; Pharmacology; Medicine; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000533618,0.0003018944,0.0003064119,0.0002261399,0.0001476056,0.0003473988,0.0002316321,0.0003457576,0.0017667],"category_scores_gemma":[0.0004851595,0.0001090948,0.000257591,0.000133463,0.0001997962,0.0001980195,0.0001292507,0.0004353262,0.0004033129],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002244001,"about_ca_system_score_gemma":0.0003613807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002713299,"about_ca_topic_score_gemma":0.0003235346,"domain_scores_codex":[0.9997818,0.00009084884,0.000012462,0.00002275017,0.00005844603,0.00003373151],"domain_scores_gemma":[0.99981,0.00003254121,0.00005393878,0.00001450528,0.00004445464,0.00004450453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01675802,0.004840568,0.004818717,0.0005259458,0.0001821351,0.0005974736,0.0001547518,0.002256649,0.8357032,0.0004139848,0.001270073,0.1324786],"study_design_scores_gemma":[0.002575923,0.4109641,0.0385629,0.0001071605,0.0004886293,0.00298557,0.0002667902,0.005645861,0.5104061,0.0004213887,0.02752781,0.00004769578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909588,0.002854749,0.003284494,0.0001027961,0.00004015437,0.0002556144,0.0002405224,0.00006266967,0.002200256],"genre_scores_gemma":[0.9947119,0.001240458,0.001333901,0.0001316768,0.0000207052,0.0001211351,0.0005670781,0.00001068776,0.001862536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0017667,"threshold_uncertainty_score":0.005910218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1278320447165254,"score_gpt":0.4643908471553785,"score_spread":0.3365588024388532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}