{"id":"W2954889722","doi":"","title":"Pre-clinical safety assessment of VB4-845, an EpCAM binding immunoconjugate","year":2008,"lang":"en","type":"article","venue":"Cancer Research","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Viventia Bio (Canada)","funders":"","keywords":"Antibody; Epitope; Amino acid; Epithelial cell adhesion molecule; Biology; Immunohistochemistry; Recombinant DNA; Molecular biology; Cancer research; Pharmacology; Medicine; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002517312,0.000177436,0.0004649427,0.000206629,0.0007499078,0.00002025756,0.0006867774,0.0003555908,0.004958044],"category_scores_gemma":[0.0001472351,0.0001559774,0.0001514508,0.00033862,0.001237757,0.0001946246,0.0002435935,0.001269684,0.0002686611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001440034,"about_ca_system_score_gemma":0.0009830764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000560945,"about_ca_topic_score_gemma":0.00004657891,"domain_scores_codex":[0.9968191,0.001092138,0.0006819505,0.0004961678,0.0001560584,0.000754602],"domain_scores_gemma":[0.9983903,0.0003416804,0.0001482968,0.0007485323,0.0003013124,0.00006994429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003071655,0.0002719328,0.01611388,0.00002333235,0.0001919476,0.00001209968,0.0005907087,0.00001098762,0.9730168,0.002183025,0.001606233,0.005671902],"study_design_scores_gemma":[0.004257195,0.00240014,0.3736328,0.0001972908,0.00003286077,0.00006621251,0.0005209777,0.00002654747,0.5392376,0.0003637939,0.07880016,0.0004643333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992745,0.002901545,0.0002883062,0.0001138702,0.001145608,0.0005461304,0.0001270821,0.00004604622,0.002086431],"genre_scores_gemma":[0.9864874,0.002628569,0.0003566395,0.00003213607,0.00009035834,0.0001070103,0.00009164579,0.00003482576,0.01017145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4337792,"threshold_uncertainty_score":0.9959515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1278320447165254,"score_gpt":0.4643908471553785,"score_spread":0.3365588024388532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}