{"id":"W2954906105","doi":"10.1002/jez.2306","title":"In defense of proteins: Chaperones respond to freezing, anoxia, or dehydration stress in tissues of freeze tolerant wood frogs","year":2019,"lang":"en","type":"article","venue":"Journal of Experimental Zoology Part A Ecological and Integrative Physiology","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"HSP60; Heat shock protein; Proteome; Biology; Chaperone (clinical); Ectotherm; Amphibian; Cell biology; Endoplasmic reticulum; Dehydration; Hsp90; Chaperonin; Hsp70; Biochemistry; Ecology; Protein folding; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001791969,0.0001786969,0.0006860163,0.0000933896,0.00002367094,0.000003241949,0.0002157182,0.0001732898,0.002301572],"category_scores_gemma":[0.0001839821,0.00009870693,0.00008163509,0.0002325256,0.00046671,0.0001785853,0.0002043146,0.0002430645,0.00001949447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007019778,"about_ca_system_score_gemma":0.00001791257,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001654484,"about_ca_topic_score_gemma":0.0004148353,"domain_scores_codex":[0.998371,0.0002766937,0.0007108476,0.0002839353,0.00012216,0.0002353341],"domain_scores_gemma":[0.9991739,0.0002726296,0.0003411596,0.00009484138,0.00003497285,0.00008253905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001802345,0.001338391,0.01196936,0.000007228302,0.00001568363,0.0000120036,0.001301672,0.0001870345,0.9827202,0.0004400389,0.00007425761,0.0001317845],"study_design_scores_gemma":[0.001117296,0.009743695,0.1892036,0.00008600409,0.000006146995,0.00001465271,0.002512142,0.0001684333,0.7934002,0.003465699,0.0001224595,0.0001595808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987321,0.0001907699,0.00001004723,0.0002454244,0.0001040047,0.0003660251,0.00001431316,0.000002711585,0.0003346073],"genre_scores_gemma":[0.9986086,0.00004314436,0.0009408307,0.0002452124,0.0000288486,0.00003894537,0.000004430148,0.000003984998,0.00008599447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.18932,"threshold_uncertainty_score":0.9986104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0186521709491325,"score_gpt":0.2740401390171432,"score_spread":0.2553879680680107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}