{"id":"W2954931853","doi":"10.1158/1538-7445.am2019-2054","title":"Abstract 2054: A novel Bcl-2/Bcl-XL inhibitor APG-1252-12A as a potential therapeutic strategy for gastric carcinoma","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"BioPhage Pharma (Canada)","funders":"","keywords":"Cancer; Apoptosis; In vivo; Cancer research; Cell cycle; Cell growth; Medicine; Flow cytometry; Western blot; Cell cycle checkpoint; Cancer cell; Cell; Internal medicine; Biology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009880181,0.0005094135,0.0003489103,0.0004671401,0.000160106,0.000269738,0.0003912415,0.0003926659,0.002286969],"category_scores_gemma":[0.00004485672,0.0001330129,0.0003373084,0.0002884048,0.0001465841,0.0002386054,0.0002146877,0.000647846,0.0004806769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002322734,"about_ca_system_score_gemma":0.0002472475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007700697,"about_ca_topic_score_gemma":0.001109294,"domain_scores_codex":[0.9999617,0.000007109054,0.000002928438,0.000006214705,0.00001018835,0.00001177717],"domain_scores_gemma":[0.9999844,0.000001202289,0.000002383929,0.000001247548,0.00000316955,0.000007516852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002733256,0.00185834,0.0006936478,0.001320623,0.0001690037,0.0009212567,0.00006714456,0.001743203,0.8723428,0.001216271,0.0053146,0.1116199],"study_design_scores_gemma":[0.0045555,0.02148393,0.01019532,0.0001923662,0.0007210227,0.003313314,0.0001185978,0.01141446,0.8601372,0.0008079427,0.08695392,0.0001063785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9176402,0.05370006,0.01117569,0.001465618,0.0005004376,0.0005167407,0.0009685909,0.0007035928,0.01332896],"genre_scores_gemma":[0.971947,0.01352289,0.004760864,0.0007179978,0.0000720821,0.0002111877,0.001283635,0.00002312211,0.007461391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002286969,"threshold_uncertainty_score":0.007650673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1075152575748127,"score_gpt":0.4173584367608956,"score_spread":0.3098431791860828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}