{"id":"W2955028827","doi":"10.1021/jacs.9b05362","title":"Integrating Activity with Accessibility in Olefin Metathesis: An Unprecedentedly Reactive Ruthenium-Indenylidene Catalyst","year":2019,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Ruthenium; Catalysis; Carbene; Lability; Steric effects; Ligand (biochemistry); Metathesis; Reactivity (psychology); Medicinal chemistry; Olefin metathesis; Olefin fiber; Salt metathesis reaction; Combinatorial chemistry; Stereochemistry; Organic chemistry; Polymerization","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001157937,0.0003224076,0.0008412202,0.00001995155,0.00005919136,0.00006555014,0.001173728,0.0001381778,0.000198723],"category_scores_gemma":[0.0007128822,0.0002002383,0.0005347671,0.0004706092,0.0004426484,0.0003232011,0.0002392559,0.001447362,0.000002631206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008909066,"about_ca_system_score_gemma":0.0002997799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002174863,"about_ca_topic_score_gemma":0.0000131173,"domain_scores_codex":[0.9976945,0.000179325,0.0006059748,0.0004423794,0.0006920826,0.0003857537],"domain_scores_gemma":[0.9963955,0.0007522257,0.001644508,0.0008485544,0.0001819715,0.0001772834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003111576,0.0003075469,0.02944892,0.00004997325,0.0002016161,0.000003342828,0.001206393,0.00000685331,0.964373,0.000001005988,0.00001980116,0.004070395],"study_design_scores_gemma":[0.0007052073,0.00004370464,0.005744441,0.0001998626,0.0001353738,0.0001491408,0.005935238,0.0002320433,0.986445,0.0001356078,0.00002537154,0.0002489852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982659,0.00003252677,0.0001440122,0.0004436864,0.00005821865,0.00007471537,0.00001031768,0.00002424471,0.0009464377],"genre_scores_gemma":[0.9898919,0.000009626883,0.00963106,0.0001045783,0.0001812749,0.000004862211,0.000001338948,0.00004416193,0.0001311377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02370448,"threshold_uncertainty_score":0.8165483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01321139890005629,"score_gpt":0.2908080993652046,"score_spread":0.2775967004651483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}