{"id":"W2955038019","doi":"10.1017/s1092852919001159","title":"Keeping up with the clinical advances: depression","year":2019,"lang":"en","type":"review","venue":"CNS Spectrums","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Major depressive disorder; Glutamatergic; Medicine; Treatment-resistant depression; Opioidergic; Antidepressant; Neuroscience; Depression (economics); Mood; Psychiatry; Bioinformatics; Psychology; Anxiety; Internal medicine; Opioid; Glutamate receptor; Biology; Receptor; (+)-Naloxone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003019753,0.0007448455,0.000932218,0.001073098,0.001295633,0.004396826,0.000971434,0.003154612,0.01385222],"category_scores_gemma":[0.006830114,0.0002085533,0.0005994136,0.0009012875,0.002060764,0.005946363,0.00291892,0.007607853,0.007702725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001826122,"about_ca_system_score_gemma":0.003852576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001447964,"about_ca_topic_score_gemma":0.003285638,"domain_scores_codex":[0.9981894,0.0006446549,0.0001738588,0.0002349911,0.0005950671,0.0001620471],"domain_scores_gemma":[0.9958407,0.001290918,0.0003450753,0.0002796507,0.001367591,0.000875985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001194734,0.00009280474,0.001519117,0.002018374,0.00008052765,0.0004450093,0.000434083,0.0001322455,0.001112534,0.02477901,0.4281613,0.5411055],"study_design_scores_gemma":[0.00002724652,0.0001008541,0.001415294,0.001761251,0.00005341049,0.001279487,0.0005394088,0.0001033879,0.0002778328,0.02038979,0.9740277,0.00002430556],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002190427,0.5004408,0.003427867,0.430291,0.02936335,0.00004534387,0.0002798404,0.0003425009,0.03361887],"genre_scores_gemma":[0.03994298,0.7216647,0.008269433,0.1469917,0.04822909,0.00009214751,0.0004803842,0.0001573476,0.03417223],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01385222,"threshold_uncertainty_score":0.04634023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1220006865212726,"score_gpt":0.3954169407748436,"score_spread":0.273416254253571,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}