{"id":"W2955038926","doi":"10.1002/ddr.21562","title":"Epigenetic treatment of dermatologic disorders","year":2019,"lang":"en","type":"article","venue":"Drug Development Research","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"MitoCure","keywords":"Psoriasis; Epigenetics; Medicine; Skin cancer; Disease; Damp; Function (biology); Inflammation; Cancer; Bioinformatics; Pharmacology; Biology; Dermatology; Immunology; Pathology; Biochemistry; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002270353,0.0001392025,0.0001823411,0.00009198227,0.00007110071,0.00001170179,0.0002526212,0.00008010305,0.00009560816],"category_scores_gemma":[0.00003261695,0.0001184032,0.00006290032,0.0001196004,0.0001352642,0.0000019784,0.0001457293,0.00006423749,0.0001456721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005015453,"about_ca_system_score_gemma":0.0002314801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002288792,"about_ca_topic_score_gemma":0.00005712823,"domain_scores_codex":[0.9986508,0.0001071953,0.0002300403,0.0003724699,0.0002445726,0.0003948756],"domain_scores_gemma":[0.9993538,0.00003802825,0.00004780236,0.0003509612,0.0001269251,0.00008248791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001494154,0.0005538748,0.2245311,0.0001150646,0.0001675826,0.000002298516,0.001164154,0.00004233727,0.7482728,0.0001129196,0.002032568,0.02285585],"study_design_scores_gemma":[0.0005326269,0.000145361,0.02141609,0.000009999522,0.000002220326,0.000001253827,0.0003156519,0.000006465525,0.8625697,0.0001691844,0.1146927,0.0001387938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932535,0.001248571,0.00006293645,0.0001810141,0.00006760778,0.0004327051,0.00000570718,0.000005667298,0.004742243],"genre_scores_gemma":[0.9939088,0.0008885945,0.001248744,0.00002203898,0.00003336696,0.00006685553,0.0001239176,0.00001590737,0.003691813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.203115,"threshold_uncertainty_score":0.4828343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02740038662406544,"score_gpt":0.3233685028904396,"score_spread":0.2959681162663741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}