{"id":"W2955057356","doi":"10.1038/s41379-019-0302-0","title":"A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases","year":2019,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Health Services; Royal Alexandra Hospital; Vancouver General Hospital; University of British Columbia; BC Cancer Agency; Foothills Medical Centre; University of Calgary","funders":"National Cancer Institute; National Institutes of Health; Medical Research Council; Universität Heidelberg; Swedish Cancer Foundation; Cancer Research Society; NSW Ministry of Health; University of New South Wales; Ovarian Cancer Action; National Institute for Health and Care Research; Translational Cancer Research Network; National Health and Medical Research Council; Cancer Research UK; National Center for Research Resources; Cancer Institute NSW; Medical Research and Materiel Command; University of Pittsburgh","keywords":"Medicine; CDX2; PAX8; Pathology; Tissue microarray; Mucinous Tumor; Mucinous carcinoma; Immunohistochemistry; Ovarian tumor; Ovarian cancer; Adenocarcinoma; Internal medicine; Cancer; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001058188,0.0007410135,0.0008608317,0.002983021,0.0003007984,0.0006620015,0.000435626,0.0007536777,0.001645045],"category_scores_gemma":[0.001076329,0.0004339404,0.0004949272,0.00104776,0.0004817207,0.0009066996,0.0005714189,0.0006366152,0.0007940381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002596341,"about_ca_system_score_gemma":0.0003345914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004451858,"about_ca_topic_score_gemma":0.001894099,"domain_scores_codex":[0.9993192,0.0001647779,0.00005792822,0.00009776044,0.0002602618,0.0001001375],"domain_scores_gemma":[0.9990702,0.0002653585,0.0001716559,0.00006261228,0.0002834406,0.0001468108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001194797,0.0001748315,0.1848039,0.000431457,0.0005103718,0.0007923517,0.0000638304,0.0004058307,0.746864,0.0002655674,0.001007722,0.06348542],"study_design_scores_gemma":[0.0001694296,0.002443926,0.4789281,0.0001675468,0.001062172,0.0201468,0.0003936795,0.01569268,0.4680661,0.001024811,0.01178971,0.0001152011],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9294423,0.03293814,0.02360656,0.0007361561,0.0003494337,0.000141834,0.0006516765,0.000488554,0.01164534],"genre_scores_gemma":[0.9799192,0.004203396,0.01259877,0.0001436285,0.0001714715,0.00008181769,0.001018368,0.00002632235,0.001837081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002983021,"threshold_uncertainty_score":0.00559634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008470072828496211,"score_gpt":0.2262015880848205,"score_spread":0.2177315152563243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}