{"id":"W2955129184","doi":"10.1038/s41374-019-0284-z","title":"A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study","year":2019,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Natural Science Foundation of China","keywords":"In vivo; Bacterial adhesin; Annexin A2; Microbiology; Biology; Adhesion; Bacterial disease; Cell biology; Annexin; Endothelial stem cell; Pathogenesis; Pathogen; Endothelium; Bacteria; Intracellular parasite; Endothelial activation; Inflammation; Immunology; Intracellular; In vitro; Chemistry; Escherichia coli; Flow cytometry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003776774,0.0001731289,0.0003157271,0.0002064043,0.00004257571,0.00004644168,0.0001594794,0.0001733502,0.00007024282],"category_scores_gemma":[0.0004799598,0.0001691382,0.00002854627,0.0003023207,0.0000502766,0.0006599174,0.00005553356,0.0001168716,0.00001677088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007426825,"about_ca_system_score_gemma":0.0003034507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004553703,"about_ca_topic_score_gemma":0.003978772,"domain_scores_codex":[0.9985445,0.0003901792,0.0003791845,0.0004314163,0.00004754886,0.0002072084],"domain_scores_gemma":[0.9990538,0.0003387089,0.0001557917,0.0002798934,0.0001123129,0.00005953179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003280283,0.0000813244,0.3091684,0.00002280074,0.00001684658,4.813944e-7,0.003094804,0.0000437688,0.6871124,0.000009277784,0.00005696692,0.00006492791],"study_design_scores_gemma":[0.002404513,0.0006563526,0.1578143,0.0002171236,0.00003276225,2.277063e-7,0.0006998922,0.00003839,0.8375638,0.0001769631,0.0002293065,0.000166361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971557,0.0005881237,0.00003790406,0.00002774081,0.0005277334,0.001306208,0.0003206317,0.00003481142,0.000001147477],"genre_scores_gemma":[0.9990281,0.0000178536,0.0005974307,0.000100393,0.00008935198,0.00006634813,0.00005701363,0.00002346201,0.00002004117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1513541,"threshold_uncertainty_score":0.6897258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01754916262800349,"score_gpt":0.2671202384962195,"score_spread":0.249571075868216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}