{"id":"W2955129184","doi":"10.1038/s41374-019-0284-z","title":"A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study","year":2019,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Natural Science Foundation of China","keywords":"In vivo; Bacterial adhesin; Annexin A2; Microbiology; Biology; Adhesion; Bacterial disease; Cell biology; Annexin; Endothelial stem cell; Pathogenesis; Pathogen; Endothelium; Bacteria; Intracellular parasite; Endothelial activation; Inflammation; Immunology; Intracellular; In vitro; Chemistry; Escherichia coli; Flow cytometry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002671056,0.00026595,0.0001942543,0.0003420499,0.0004298597,0.0007840747,0.0005301688,0.0007614284,0.002156952],"category_scores_gemma":[0.0002462504,0.0001825066,0.0001884926,0.0001702985,0.0004953948,0.001179776,0.0004062759,0.0006618208,0.0003825632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000391442,"about_ca_system_score_gemma":0.0002055926,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009492569,"about_ca_topic_score_gemma":0.000766388,"domain_scores_codex":[0.9998783,0.00002684809,0.000006366079,0.00002493146,0.00003202804,0.00003158148],"domain_scores_gemma":[0.9997533,0.00008365591,0.00002846998,0.00004059511,0.00004725581,0.00004664063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001282416,0.00004768711,0.000590786,0.00003788776,0.000006300581,0.0002808729,0.00004685368,0.00005631108,0.996073,0.00142137,0.00008432022,0.001226405],"study_design_scores_gemma":[0.00003981725,0.0004591427,0.009969087,0.00001458453,0.00001890837,0.001391128,0.0003645219,0.003844701,0.9726168,0.001712945,0.009547865,0.00002063853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9601296,0.003018802,0.02800719,0.0008543229,0.0001111515,0.00005622905,0.0002286347,0.0001525304,0.007441574],"genre_scores_gemma":[0.9856451,0.00105994,0.008971523,0.000150333,0.00003375026,0.00002334966,0.0001881885,0.00001848212,0.003909484],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002156952,"threshold_uncertainty_score":0.007215679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01754916262800349,"score_gpt":0.2671202384962195,"score_spread":0.249571075868216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}