{"id":"W2955262879","doi":"10.1002/mus.26617","title":"Amyotrophic lateral sclerosis: Origins traced to impaired balance between neural excitation and inhibition in the neonatal period","year":2019,"lang":"en","type":"review","venue":"Muscle & Nerve","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Amyotrophic lateral sclerosis; Neuroscience; Excitotoxicity; Neurodegeneration; Inhibitory postsynaptic potential; Medicine; Disease; Prodrome; Excitatory postsynaptic potential; Psychology; Pathology; Glutamate receptor; Internal medicine; Psychiatry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003310617,0.0007097204,0.0008893662,0.002169485,0.0002446701,0.0007987532,0.0006435507,0.0007617188,0.003436376],"category_scores_gemma":[0.0004984083,0.0001544084,0.0003021504,0.002103346,0.0005208965,0.00113106,0.0005474156,0.001067796,0.002233917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005731471,"about_ca_system_score_gemma":0.0009480616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086045,"about_ca_topic_score_gemma":0.00216821,"domain_scores_codex":[0.9999102,0.00001487382,0.00001512255,0.0000179885,0.00003118274,0.00001052658],"domain_scores_gemma":[0.9998323,0.00006885002,0.00003079819,0.00000581871,0.00004260969,0.00001974641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007531005,0.00003384621,0.0002325244,0.01490669,0.00005040508,0.0003110437,0.00008029315,0.0001796907,0.001353124,0.003474425,0.02528551,0.954017],"study_design_scores_gemma":[0.00001248621,0.00007971054,0.001591624,0.008457159,0.0001076669,0.003041929,0.0001286915,0.00004873216,0.0003271883,0.00304752,0.9831419,0.00001548091],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005864916,0.9991309,0.00002480457,0.0001430199,0.00008942451,9.344219e-7,0.000005634786,0.000002931708,0.0005437759],"genre_scores_gemma":[0.0004723012,0.9989821,0.0000476342,0.00008456504,0.0000736169,0.000001551663,0.00001006232,5.604053e-7,0.0003275692],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003436376,"threshold_uncertainty_score":0.01149583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.107513182659815,"score_gpt":0.3497580072672617,"score_spread":0.2422448246074467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}