{"id":"W2955264692","doi":"10.1200/jco.2019.37.15_suppl.7059","title":"Results from ongoing phase 1/2 clinical trial of tagraxofusp (SL-401) in patients with relapsed/refractory chronic myelomonocytic leukemia (CMML).","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; Alberta Hospital Edmonton; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Nausea; Chronic myelomonocytic leukemia; Refractory (planetary science); Internal medicine; Gastroenterology; Vomiting; Interleukin-3 receptor; Malignancy; Stage (stratigraphy); Leukemia; Oncology; Bone marrow; Myelodysplastic syndromes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001848405,0.001299127,0.001211294,0.0002470126,0.0003451051,0.0006331381,0.000554602,0.001229481,0.004613606],"category_scores_gemma":[0.0007759406,0.0003747611,0.0007399003,0.000230572,0.0004788227,0.000736076,0.0002436318,0.002025435,0.0008986557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006307377,"about_ca_system_score_gemma":0.001019904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009497661,"about_ca_topic_score_gemma":0.002769729,"domain_scores_codex":[0.9996823,0.0001575572,0.00002107866,0.00004013638,0.00003480558,0.0000641407],"domain_scores_gemma":[0.9994493,0.0001087963,0.0001023347,0.0000409616,0.00003847253,0.0002601309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6176953,0.06785578,0.01693716,0.001256326,0.001924893,0.0005344723,0.0003856134,0.003261554,0.0823274,0.0003814741,0.02159294,0.185847],"study_design_scores_gemma":[0.5320692,0.4112637,0.04107704,0.00008539666,0.0007697554,0.0006718602,0.00007259052,0.00138917,0.005054473,0.0002911371,0.007221759,0.00003393021],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818056,0.003332198,0.0007313676,0.001181308,0.0001575377,0.003496461,0.005295678,0.0001728491,0.003827023],"genre_scores_gemma":[0.9709007,0.002763294,0.002637778,0.002099442,0.0002221528,0.003770162,0.01301175,0.00004528686,0.004549541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004613606,"threshold_uncertainty_score":0.01543409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1029157698071348,"score_gpt":0.465666030387402,"score_spread":0.3627502605802672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}