{"id":"W2955409178","doi":"10.1107/s2053230x19007726","title":"Structural characterization of <i>Treponema pallidum</i> Tp0225 reveals an unexpected leucine-rich repeat architecture","year":2019,"lang":"en","type":"article","venue":"Acta Crystallographica Section F Structural Biology Communications","topic":"Syphilis Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Institute of Infection and Immunity; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Treponema; Biology; Pathogen; Leucine-rich repeat; Architecture domain; Human pathogen; Genetics; Bacteria; Microbiology; Gene; Syphilis; Virology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009979691,0.0003303766,0.0001847477,0.0002004186,0.0001614203,0.0003660699,0.0003659797,0.0003441558,0.001184981],"category_scores_gemma":[0.0002332524,0.0001287311,0.0002497273,0.0003054503,0.0001630001,0.000186865,0.0001642,0.0003491036,0.0003134801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003006874,"about_ca_system_score_gemma":0.0002550543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002949948,"about_ca_topic_score_gemma":0.002387823,"domain_scores_codex":[0.9999435,0.000004799499,0.00000229662,0.00001378381,0.0000240509,0.00001159404],"domain_scores_gemma":[0.9999334,0.00001122363,0.00002149574,0.000004951258,0.000009140821,0.00001981091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002892017,0.00004064157,0.003235229,0.0001224562,0.00002701208,0.001028156,0.0001016635,0.0012046,0.9881478,0.0003492228,0.0007768348,0.004677224],"study_design_scores_gemma":[0.0001869563,0.001300617,0.2517631,0.0001239562,0.0002230618,0.006124943,0.0007097865,0.04839306,0.6494007,0.0006940071,0.04094577,0.0001340394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951083,0.0008641251,0.001322476,0.0001227882,0.00001899904,0.00001415186,0.0006319775,0.0001040735,0.001813124],"genre_scores_gemma":[0.9941102,0.000494985,0.002113883,0.00006181063,0.00001092361,0.000007897354,0.002201395,0.000021456,0.0009774861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002949948,"threshold_uncertainty_score":0.005865574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02096813921046518,"score_gpt":0.2862965306279412,"score_spread":0.265328391417476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}