{"id":"W2955504395","doi":"10.1186/s12974-019-1523-3","title":"T cell-selective deletion of Oct1 protects animals from autoimmune neuroinflammation while maintaining neurotropic pathogen response","year":2019,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; Praespero; National Multiple Sclerosis Society","keywords":"Neuroinflammation; Neuroscience; Neurology; Microglia; Immunology; Medicine; Pathogen; Biology; Inflammation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008294905,0.0002934539,0.0006353966,0.0004768493,0.000142763,0.00003400427,0.0003712932,0.0003074915,0.0002466203],"category_scores_gemma":[0.0004151845,0.0002719186,0.0002443303,0.0003133459,0.0001002753,0.0004425218,0.00009591509,0.0007752294,0.0002979821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009432393,"about_ca_system_score_gemma":0.0002169241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003006043,"about_ca_topic_score_gemma":0.000002220888,"domain_scores_codex":[0.9962345,0.001556094,0.001346815,0.0003242232,0.000168156,0.0003701777],"domain_scores_gemma":[0.9963312,0.0005746443,0.002172972,0.0003952601,0.0004926763,0.00003329762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004380481,0.0001113149,0.0007560754,0.00003725696,0.00008373698,0.00003316275,0.0007085308,0.0006967882,0.9916177,0.0001088219,0.0001752243,0.001290859],"study_design_scores_gemma":[0.002938691,0.002479783,0.06690771,0.0001079882,0.00008057942,0.0002914862,0.0001727949,0.0001915407,0.9233395,0.0003449001,0.002933292,0.0002116743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963712,0.0007786527,0.000356172,0.000310724,0.001014463,0.0006906582,0.00001693482,0.00004989599,0.000411323],"genre_scores_gemma":[0.9991421,0.00008072996,0.0002427216,0.00002189372,0.00008600035,0.000009246779,0.00004039538,0.00004143107,0.0003354626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06827819,"threshold_uncertainty_score":0.9999733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01021360568543114,"score_gpt":0.2107827256845005,"score_spread":0.2005691199990694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}