{"id":"W2955532382","doi":"10.1016/j.jval.2019.04.552","title":"PDB2 COMPARATIVE EFFICACY AND SAFETY OF PHARMACOTHERAPIES FOR THE TREATMENT OF OBESITY AMONG ADULTS: A SYSTEMATLIC LITERATURE AND NETWORK META-ANALYSIS","year":2019,"lang":"en","type":"article","venue":"Value in Health","topic":"Pharmacology and Obesity Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Precision Nanosystems (Canada)","funders":"","keywords":"Medicine; Phentermine; Orlistat; Liraglutide; Bupropion; Placebo; Topiramate; Overweight; Internal medicine; Meta-analysis; Subgroup analysis; Adverse effect; Obesity; Weight loss; Type 2 diabetes; Diabetes mellitus; Smoking cessation; Endocrinology; Epilepsy; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.012516,0.001880309,0.007061625,0.003164771,0.0006980301,0.003039793,0.00146891,0.002186448,0.006439054],"category_scores_gemma":[0.03204432,0.001075375,0.02941532,0.003588143,0.0008009425,0.001339865,0.002184278,0.002632643,0.0005083416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001274992,"about_ca_system_score_gemma":0.001130881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007059459,"about_ca_topic_score_gemma":0.01058464,"domain_scores_codex":[0.9869731,0.008156683,0.001859081,0.001595996,0.001003373,0.0004117866],"domain_scores_gemma":[0.9810627,0.01409572,0.002297451,0.001335051,0.0009304773,0.0002786205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01357577,0.00004617958,0.01530543,0.01774694,0.9467633,0.00006533329,0.00005962579,0.0004375326,0.0002962524,0.0001948116,0.0005130517,0.004995819],"study_design_scores_gemma":[0.003496471,0.0003308527,0.009756865,0.001044139,0.9832622,0.00005937023,0.00003954092,0.0003719266,0.0001245252,0.0003472982,0.001146416,0.00002033981],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1941074,0.7835118,0.007464714,0.001565772,0.001412848,0.000684304,0.006978826,0.0002135769,0.004060901],"genre_scores_gemma":[0.9419545,0.04859137,0.003399341,0.00129176,0.0005014802,0.0005921546,0.002124527,0.00009106786,0.001453771],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9929384,"threshold_uncertainty_score":0.06619173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08286185006423652,"score_gpt":0.3746949147785509,"score_spread":0.2918330647143144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}