{"id":"W2955588583","doi":"10.1371/journal.ppat.1007850","title":"The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors","year":2019,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council Centre for Medical Mycology; UK Dementia Research Institute; National Institutes of Health; Kidney Research UK; University of Aberdeen; Parc Geneteg Cymru; International Seafood Sustainability Foundation; Wellcome Trust; National Institute of General Medical Sciences; Medical Research Council; Wellcome","keywords":"Candida albicans; C-type lectin; Immune system; Innate immune system; Corpus albicans; Immunology; Pattern recognition receptor; Biology; Systemic candidiasis; Microbiology; Monocyte; Acquired immune system; Receptor; Chemokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002478477,0.0005247524,0.0004245548,0.0002494712,0.0001905185,0.0003781298,0.0001963424,0.0003764272,0.0009056958],"category_scores_gemma":[0.0001546022,0.0002015653,0.0003214087,0.00009993642,0.0002967581,0.0002778778,0.0003588355,0.0009918847,0.0003039939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002246818,"about_ca_system_score_gemma":0.0003028163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003235851,"about_ca_topic_score_gemma":0.0005493925,"domain_scores_codex":[0.9995685,0.00007316429,0.00004395268,0.00008453345,0.00007354171,0.0001563407],"domain_scores_gemma":[0.9997676,0.00001475995,0.00007302034,0.00002953256,0.00002625177,0.0000887998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005506075,0.00003641836,0.0005451276,0.00006422067,0.000004293741,0.0001390752,0.0000239668,0.00003351633,0.996712,0.00009592508,0.00004123236,0.001753602],"study_design_scores_gemma":[0.0001245673,0.001631337,0.05319162,0.00007640647,0.00008146584,0.001908803,0.0002465521,0.00136742,0.9379033,0.0002425096,0.003202029,0.00002401715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926104,0.002609849,0.002501799,0.0002264031,0.00005463948,0.00004300235,0.0003275328,0.00009508333,0.001531332],"genre_scores_gemma":[0.9947412,0.0009842961,0.002187437,0.000149377,0.00002184208,0.00007126688,0.0002164442,0.00001418828,0.001613917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009056958,"threshold_uncertainty_score":0.003029823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0111193701510462,"score_gpt":0.2583565768908834,"score_spread":0.2472372067398372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}