{"id":"W2955744765","doi":"10.1152/ajpgi.00186.2019","title":"Acute regulation of intestinal ion transport and permeability in response to luminal nutrients: the role of the enteric nervous system","year":2019,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Institute of Health Services and Policy Research; Government of Canada; Human Frontier Science Program; Canadian Institutes of Health Research; Alberta Innovates - Health Solutions; Natural Sciences and Engineering Research Council of Canada","keywords":"Veratridine; Enteric nervous system; Tetrodotoxin; Ileum; Intestinal permeability; Ussing chamber; Jejunum; Glutamine; Small intestine; Permeability (electromagnetism); Lipopolysaccharide; Chemistry; Barrier function; Internal medicine; Biology; Endocrinology; Biophysics; Biochemistry; Cell biology; Sodium; Sodium channel; Secretion; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001933748,0.0003863742,0.0005244611,0.0001692401,0.0001646424,0.0004537725,0.0002552772,0.0006225505,0.0007182135],"category_scores_gemma":[0.0002261532,0.0001749607,0.0003389938,0.000142608,0.000527708,0.0008645258,0.0003517686,0.0009732646,0.0001357312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004366691,"about_ca_system_score_gemma":0.0002368994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003204757,"about_ca_topic_score_gemma":0.0004131518,"domain_scores_codex":[0.9998622,0.00002986316,0.00001564165,0.00003109539,0.00002573516,0.00003549695],"domain_scores_gemma":[0.9998084,0.000031907,0.00006051214,0.00001768719,0.00002691004,0.00005455556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005854356,0.0000255373,0.0005564872,0.0001699459,0.000009984847,0.0001977112,0.0000284036,0.00003210732,0.996558,0.00007339149,0.00002373506,0.001739282],"study_design_scores_gemma":[0.00008801914,0.002255381,0.07864759,0.00004872477,0.00009390405,0.0007971445,0.0002222246,0.00101646,0.9138259,0.0003224858,0.002658287,0.00002392146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788255,0.0161257,0.003281626,0.0004108426,0.00006594048,0.00003230373,0.0001341491,0.00007024095,0.001053781],"genre_scores_gemma":[0.9915481,0.004767739,0.002307556,0.0001779214,0.00004487844,0.0000503438,0.0001159796,0.000009934167,0.000977528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007182135,"threshold_uncertainty_score":0.003168225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00430342084998718,"score_gpt":0.2097213893851967,"score_spread":0.2054179685352095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}