{"id":"W2955755622","doi":"10.3747/co.26.4381","title":"Fatal Myocarditis and Rhabdomyositis in a Patient with Stage Iv Melanoma Treated with Combined Ipilimumab and Nivolumab","year":2019,"lang":"en","type":"article","venue":"Current Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Nivolumab; Ipilimumab; Medicine; Myocarditis; Melanoma; Internal medicine; Stage (stratigraphy); Metastatic melanoma; Oncology; Dermatology; Immunotherapy; Cancer research; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003649763,0.001120231,0.0007622554,0.0007969611,0.001779724,0.0007500048,0.0005499204,0.002387004,0.0007848843],"category_scores_gemma":[0.001418308,0.0007717663,0.001050795,0.0003718692,0.0008694838,0.0005759724,0.000654545,0.001717128,0.0003119328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001140503,"about_ca_system_score_gemma":0.0005198298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001799939,"about_ca_topic_score_gemma":0.003146091,"domain_scores_codex":[0.9996502,0.00007460625,0.00003960468,0.00008285375,0.00004472025,0.0001080791],"domain_scores_gemma":[0.9993078,0.0001861597,0.0001221431,0.0000524162,0.00003595291,0.0002955668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0003349585,0.0001486393,0.02605705,0.00005001986,0.00006382397,0.964999,0.0003008103,0.000380742,0.004290862,0.0001786887,0.0003172675,0.002878205],"study_design_scores_gemma":[0.00012923,0.001132754,0.03671503,0.00004104308,0.0001116528,0.955982,0.0001856771,0.001943996,0.002585376,0.0002184482,0.0009260569,0.00002866789],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879547,0.001828981,0.001919536,0.001530634,0.0001323954,0.0001090162,0.00009078266,0.0001133293,0.006320667],"genre_scores_gemma":[0.9980101,0.0004007652,0.0003795954,0.0004632252,0.0001408021,0.00001037229,0.00003863983,0.000008326761,0.0005483681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002387004,"threshold_uncertainty_score":0.008274972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0286799807258527,"score_gpt":0.3228566247099005,"score_spread":0.2941766439840477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}