{"id":"W2955755622","doi":"10.3747/co.26.4381","title":"Fatal Myocarditis and Rhabdomyositis in a Patient with Stage Iv Melanoma Treated with Combined Ipilimumab and Nivolumab","year":2019,"lang":"en","type":"article","venue":"Current Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Nivolumab; Ipilimumab; Medicine; Myocarditis; Melanoma; Internal medicine; Stage (stratigraphy); Metastatic melanoma; Oncology; Dermatology; Immunotherapy; Cancer research; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001441114,0.0002126022,0.0005987007,0.0002151443,0.00004036215,0.00002033564,0.00005738342,0.0001103404,0.0005478595],"category_scores_gemma":[0.00001578948,0.0001577518,0.00002918993,0.0002378534,0.0002605063,0.00007542558,0.00008253723,0.0003874654,0.00001822269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003187031,"about_ca_system_score_gemma":0.0002237544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002019351,"about_ca_topic_score_gemma":0.0003704625,"domain_scores_codex":[0.9984592,0.0001467833,0.0002218094,0.0004602898,0.0002800985,0.0004318288],"domain_scores_gemma":[0.9991822,0.000146506,0.00007625246,0.000281289,0.00009809626,0.0002156115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009436588,0.000729872,0.7476976,0.000233062,0.0001736511,0.001125793,0.001281955,0.000002405906,0.003393852,0.00006578574,0.0002528281,0.2356066],"study_design_scores_gemma":[0.08495504,0.07140845,0.7354375,0.0007907278,0.0002165274,0.003190794,0.002253965,0.001593401,0.002353186,0.00002657546,0.0970349,0.0007388951],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941585,0.0009527022,0.00001078509,0.0002783773,0.0001019192,0.001377196,0.00003645508,0.00003694485,0.003047141],"genre_scores_gemma":[0.9984574,0.0003769593,0.00009406883,0.00005112901,0.00003645484,0.0000928442,0.00008740431,0.00003383057,0.0007698496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2348677,"threshold_uncertainty_score":0.6432931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0286799807258527,"score_gpt":0.3228566247099005,"score_spread":0.2941766439840477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}