{"id":"W2955783168","doi":"10.1016/j.cbi.2019.108739","title":"Caution for the routine use of phenol red – It is more than just a pH indicator","year":2019,"lang":"en","type":"article","venue":"Chemico-Biological Interactions","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Gips-Schüle-Stiftung","keywords":"Myeloperoxidase; Chemistry; Peroxidase; Biochemistry; Glutathione; Hydrogen peroxide; Metabolite; Viability assay; Intracellular; Cell culture; Phenol red; Cytotoxicity; Lactoperoxidase; Horseradish peroxidase; Molecular biology; Enzyme; Cell; Chromatography; In vitro; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001213776,0.0002067367,0.0003243791,0.00006294733,0.0001813697,0.00001627113,0.0002853124,0.0002575999,0.003017481],"category_scores_gemma":[0.0001722574,0.0001246812,0.00023023,0.0001264276,0.0002337066,0.0001339135,0.0001250759,0.0003848609,0.0003800767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005416136,"about_ca_system_score_gemma":0.00002508158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003772244,"about_ca_topic_score_gemma":0.0000051883,"domain_scores_codex":[0.9988629,0.00007000678,0.0003608277,0.0003748496,0.00003083814,0.0003006357],"domain_scores_gemma":[0.9985013,0.0007141161,0.0002452365,0.0003924767,0.0001211686,0.00002570488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002906462,0.0001677601,0.0009119724,0.00001141305,0.0002189685,4.674703e-7,0.0003687586,0.000002088517,0.9797586,0.0009599429,0.01690174,0.0004076677],"study_design_scores_gemma":[0.0007057844,0.000209546,0.001843517,0.00003624705,0.00007171818,0.00002685935,0.0009883351,0.0000242561,0.857083,0.000140697,0.1387163,0.0001538424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920722,0.0001920839,0.000750099,0.004714536,0.0007638406,0.0007308493,0.0003440182,0.00006212308,0.0003702927],"genre_scores_gemma":[0.9929619,0.00008673411,0.000153845,0.001582972,0.00006470907,0.0001528841,0.0003791997,0.00001452255,0.004603276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1226756,"threshold_uncertainty_score":0.9978939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08287951567619394,"score_gpt":0.3101397703738735,"score_spread":0.2272602546976795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}