{"id":"W2955792169","doi":"10.1080/19336950.2019.1638695","title":"pHluorin-tagged TRPV1 shines light on capsaicin tachyphylaxis","year":2019,"lang":"en","type":"letter","venue":"Channels","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Capsaicin; Tachyphylaxis; TRPV1; Chemistry; Transient receptor potential channel; Cell biology; Biology; Pharmacology; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005228703,0.0005202122,0.0004925437,0.000223308,0.0007936304,0.0009767634,0.0004132754,0.005832267,0.006863008],"category_scores_gemma":[0.001953999,0.0001929337,0.0004934843,0.0001174315,0.001008597,0.0006615858,0.0003775364,0.005376909,0.003019534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001207311,"about_ca_system_score_gemma":0.000402504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008941636,"about_ca_topic_score_gemma":0.001561621,"domain_scores_codex":[0.9997423,0.00004469648,0.00001945292,0.00004404434,0.00009412179,0.00005533789],"domain_scores_gemma":[0.9994078,0.0003654557,0.00004875873,0.00003664859,0.00007093095,0.00007056115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003269072,0.0004205481,0.001653866,0.0003974162,0.0001090907,0.01777149,0.0002093202,0.0005033806,0.06125851,0.01352776,0.7975371,0.1033423],"study_design_scores_gemma":[0.001065131,0.001351213,0.007563414,0.0003092956,0.0001659622,0.01003136,0.0004367987,0.003556997,0.07121776,0.02530032,0.8788587,0.0001431218],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.04021234,0.01542815,0.003071807,0.7735792,0.0932206,0.0001006439,0.0004647326,0.0005660061,0.07335643],"genre_scores_gemma":[0.342105,0.01571832,0.002883256,0.4451443,0.07118908,0.0001984086,0.0003307837,0.0001575563,0.1222733],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006863008,"threshold_uncertainty_score":0.02295899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04030683450160799,"score_gpt":0.259688859439395,"score_spread":0.219382024937787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}