{"id":"W2955828947","doi":"10.1158/1538-7445.pedca19-a45","title":"Abstract A45: Targeted drug therapies for osteosarcoma","year":2020,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"PTEN; Medicine; Disease; Cancer; Cancer research; Somatic cell; Oncology; Bioinformatics; PI3K/AKT/mTOR pathway; Internal medicine; Biology; Genetics; Gene; Signal transduction","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003732204,0.0004684136,0.0004514405,0.0008050841,0.0002411564,0.0008375391,0.0003225675,0.0006115375,0.00527921],"category_scores_gemma":[0.000185109,0.0001619607,0.0007498818,0.0005243332,0.0002178898,0.0003937032,0.0004647583,0.0009139921,0.001629882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004803989,"about_ca_system_score_gemma":0.0005506859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009346727,"about_ca_topic_score_gemma":0.001833761,"domain_scores_codex":[0.9998006,0.00003367763,0.0000159874,0.00003552046,0.00007864561,0.00003559588],"domain_scores_gemma":[0.9999136,0.000009186486,0.00001544919,0.000007951878,0.00002100599,0.00003283914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001899714,0.001885326,0.001901648,0.001529265,0.0002957257,0.0006442689,0.0001283069,0.002615112,0.6844405,0.00736699,0.0179671,0.2793262],"study_design_scores_gemma":[0.001969935,0.02191984,0.01850956,0.0005120895,0.0006891036,0.003637381,0.0001103671,0.00635189,0.4492066,0.004066307,0.4929146,0.0001123137],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.6416695,0.231702,0.03647445,0.005424928,0.00322753,0.001598267,0.008677502,0.001664112,0.06956169],"genre_scores_gemma":[0.8381497,0.09876052,0.01884762,0.003874143,0.0003650858,0.000485657,0.008182336,0.0002010056,0.03113386],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.00527921,"threshold_uncertainty_score":0.01766074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05939502512736048,"score_gpt":0.3695825417474782,"score_spread":0.3101875166201177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}