{"id":"W2955948108","doi":"10.1002/ijc.32555","title":"Circulating markers of cellular immune activation in prediagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)","year":2019,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Division of Cancer Epidemiology and Genetics, National Cancer Institute; National Cancer Institute; National Heart, Lung, and Blood Institute; Faculty of Medicine and Health, University of Sydney; Norges Forskningsråd; National Health and Medical Research Council; Medical Research Council; National Institute on Drug Abuse; York University; Cancer Council Victoria; Norges Teknisk-Naturvitenskapelige Universitet; New York City Department of Health and Mental Hygiene; World Health Organization; Centre International de Recherche sur le Cancer; Women's Health Initiative; Norwegian Institute of Public Health; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Lung cancer; Medicine; Neopterin; Internal medicine; Oncology; Kynurenine; Cancer; Prospective cohort study; Odds ratio; Cohort; Cohort study; Gastroenterology; Immunology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00154303,0.0002925628,0.0003194947,0.000670164,0.0005009138,0.0007138246,0.0004021941,0.0006273196,0.0009914148],"category_scores_gemma":[0.002345116,0.0002033048,0.0006104364,0.001131493,0.0002477681,0.0002024906,0.0004627355,0.0006177126,0.0001823748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004257172,"about_ca_system_score_gemma":0.0004469269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01669892,"about_ca_topic_score_gemma":0.02015419,"domain_scores_codex":[0.999249,0.000209345,0.00007307078,0.0002111387,0.0001429462,0.0001145127],"domain_scores_gemma":[0.9982471,0.0003129696,0.0006681049,0.0003113588,0.0002433603,0.000217065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003573938,0.00002566121,0.9970509,0.000009591355,0.00009458476,0.00005214722,0.00003209151,0.00006384679,0.001315735,0.00001576719,0.0001557503,0.0008264674],"study_design_scores_gemma":[0.00001816344,0.00007793122,0.9986883,0.0000028474,0.00005126833,0.0002243682,0.00002817617,0.0001845493,0.0004392671,0.00001766264,0.0002639572,0.000003474191],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997296,0.0002391001,0.0004589206,0.00004178717,0.000007796926,0.00001928181,0.001508691,0.00001672677,0.0004115871],"genre_scores_gemma":[0.9978045,0.00004632558,0.0003484134,0.00003657808,0.000008029729,0.00002811142,0.001484527,0.000006236824,0.0002371952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01669892,"threshold_uncertainty_score":0.03320348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008661705142776857,"score_gpt":0.2846055497957305,"score_spread":0.2759438446529536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}