{"id":"W2955954677","doi":"10.1158/1538-7445.am2019-2699","title":"Abstract 2699: Targeting an ubiquitin-activating enzyme in small-cell lung cancer (SCLC)","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Etoposide; Cancer research; Cancer; Lung cancer; Cisplatin; Medicine; Viability assay; Cell culture; Cancer cell; Chemotherapy; Cell; Biology; Oncology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002770159,0.0003215421,0.0006183657,0.0006162483,0.0002859591,0.0001219856,0.0005085537,0.000182614,0.003187613],"category_scores_gemma":[0.0004923607,0.0002862703,0.0001071573,0.001231377,0.0002309215,0.0003713773,0.0004436548,0.002209036,0.0001187391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002489441,"about_ca_system_score_gemma":0.002045198,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01580186,"about_ca_topic_score_gemma":0.002088515,"domain_scores_codex":[0.9948934,0.0002929172,0.00053612,0.0009968253,0.001413599,0.001867173],"domain_scores_gemma":[0.9973603,0.0005460588,0.0001186943,0.0006947796,0.0008033848,0.0004768045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009940413,0.0003480829,0.3062997,0.003269775,0.0001699613,0.0002974849,0.004461559,0.0005085869,0.6607881,0.00008181969,0.009165671,0.01361526],"study_design_scores_gemma":[0.0126047,0.001334773,0.2864042,0.007374966,0.00006850157,0.00001809193,0.01244466,0.00475244,0.6401257,0.0001514489,0.03314614,0.00157435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683509,0.01272292,0.000005020603,0.002237601,0.0002955553,0.002044395,0.00003400933,0.00009690826,0.01421266],"genre_scores_gemma":[0.9907132,0.002417228,0.00019379,0.0002423281,0.0009848471,0.001108587,0.00002392673,0.0001195623,0.004196548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02398047,"threshold_uncertainty_score":0.9999589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08719973509604924,"score_gpt":0.4541016868402734,"score_spread":0.3669019517442242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}