{"id":"W2955971475","doi":"10.3390/e21070662","title":"Entropy and Information within Intrinsically Disordered Protein Regions","year":2019,"lang":"en","type":"article","venue":"Entropy","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Conformational ensembles; Conformational entropy; Entropy (arrow of time); Intrinsically disordered proteins; Sequence (biology); Computer science; Biological system; Protein structure; Computational biology; Statistical physics; Physics; Chemistry; Biology; Biophysics; Molecule; Thermodynamics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001098605,0.000264532,0.0006166823,0.001627669,0.000392213,0.001024959,0.0004116334,0.0004792936,0.0005901409],"category_scores_gemma":[0.004244277,0.0002132026,0.0002722662,0.0008699881,0.001994201,0.001947616,0.0009178542,0.0005224656,0.0001310293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007075645,"about_ca_system_score_gemma":0.0003277183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005081054,"about_ca_topic_score_gemma":0.000431629,"domain_scores_codex":[0.9994559,0.0001524806,0.00004375936,0.0001397761,0.0001455937,0.00006257262],"domain_scores_gemma":[0.9961946,0.002283156,0.0008260754,0.000295253,0.0001927069,0.0002082232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0007576614,0.0001829209,0.06622045,0.0008284803,0.0004298947,0.000812026,0.001179287,0.3169564,0.1467815,0.390659,0.001886891,0.07330558],"study_design_scores_gemma":[0.00002092386,0.0001718741,0.04161762,0.00009177211,0.00005882226,0.0005148811,0.0001894314,0.4244993,0.01885938,0.5102469,0.003590095,0.0001388876],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8470618,0.004293273,0.1416437,0.0007798591,0.00008648531,0.00002311722,0.0007010326,0.0002127207,0.005198022],"genre_scores_gemma":[0.991194,0.000690161,0.007198298,0.00006774926,0.00007184255,0.00002043603,0.000264241,0.00003079675,0.000462641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001627669,"threshold_uncertainty_score":0.005810022,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002236243308019332,"score_gpt":0.1913433159782955,"score_spread":0.1891070726702762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}