{"id":"W2955982848","doi":"10.1093/annonc/mdz155.216","title":"A phase 3 study of durvalumab with or without bevacizumab as adjuvant therapy in patients with hepatocellular carcinoma at high risk of recurrence after curative hepatic resection or ablation: EMERALD-2","year":2019,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Hepatocellular carcinoma; Durvalumab; Bevacizumab; Adjuvant; Adjuvant therapy; Refractory (planetary science); Resection; Oncology; Hepatocellular cancer; Internal medicine; Ablation; Surgery; Cancer; Chemotherapy; Nivolumab; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001599696,0.001144272,0.002091058,0.0003402609,0.00032325,0.001114137,0.0007018844,0.0009580933,0.003283395],"category_scores_gemma":[0.0009257443,0.0005350643,0.002041113,0.0003645572,0.0009211944,0.00109566,0.0003518296,0.002939552,0.0006668927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001122959,"about_ca_system_score_gemma":0.001453827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001547714,"about_ca_topic_score_gemma":0.004830957,"domain_scores_codex":[0.9995959,0.0001800896,0.00001598232,0.00007722568,0.00003121167,0.00009953018],"domain_scores_gemma":[0.9995009,0.00009955194,0.00007182072,0.00005175865,0.0000294068,0.00024657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8673981,0.03342792,0.005657982,0.0005288337,0.002240629,0.0001270524,0.0002097273,0.001407245,0.01408982,0.0003047126,0.002630077,0.07197791],"study_design_scores_gemma":[0.7963814,0.1884564,0.008451869,0.00003143553,0.001046653,0.0001496906,0.00007057027,0.0009367154,0.001845622,0.000221959,0.00237234,0.00003527681],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99281,0.002580234,0.0004938904,0.0006676639,0.0002496752,0.0009635907,0.0007525861,0.00006545951,0.001416907],"genre_scores_gemma":[0.988735,0.002264078,0.001885112,0.001175267,0.0002045274,0.001432252,0.001763864,0.00004263642,0.002497209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003283395,"threshold_uncertainty_score":0.010984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07664049788847313,"score_gpt":0.3410088750915553,"score_spread":0.2643683772030821,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}