{"id":"W2955990171","doi":"10.1128/jvi.00495-19","title":"Alternate NF-κB-Independent Signaling Reactivation of Latent HIV-1 Provirus","year":2019,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Ministero della Salute","keywords":"Biology; Provirus; Human immunodeficiency virus (HIV); NF-κB; Virology; NFKB1; Signal transduction; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001315121,0.0002215475,0.0002652344,0.0001365084,0.0001148452,0.0002946238,0.0002419568,0.0001973306,0.002038681],"category_scores_gemma":[0.0001119314,0.00006502711,0.0001951383,0.00008975659,0.0001705767,0.0002138718,0.0002176284,0.0004851123,0.0003584276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001919158,"about_ca_system_score_gemma":0.0001934475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001702644,"about_ca_topic_score_gemma":0.0003280712,"domain_scores_codex":[0.9998616,0.00002549016,0.000007652335,0.00002812525,0.00002510157,0.0000519502],"domain_scores_gemma":[0.9999396,0.00001125004,0.00001529717,0.00001397742,0.000004670441,0.00001527062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003004454,0.00005652905,0.0001961574,0.00006102195,0.000006957175,0.00006442842,0.0000160211,0.00005487193,0.9960997,0.000259907,0.0000564067,0.002827545],"study_design_scores_gemma":[0.00005076529,0.0008691322,0.002881921,0.000009868414,0.00002269946,0.0004274285,0.00004348716,0.0008493142,0.9916545,0.000152327,0.003033409,0.000005112123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989729,0.003221402,0.003848699,0.00008456263,0.00005516609,0.00005172899,0.0002398089,0.00007321155,0.002696365],"genre_scores_gemma":[0.9964071,0.0007420353,0.001055566,0.00003091099,0.00001575909,0.00003417644,0.0001695484,0.000006345224,0.00153856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002038681,"threshold_uncertainty_score":0.006820083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01388973567119696,"score_gpt":0.2571754786297751,"score_spread":0.2432857429585781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}