{"id":"W2956018477","doi":"10.1093/biolre/ioz090","title":"Mice lacking membrane estrogen receptor 1 are protected from reproductive pathologies resulting from developmental estrogen exposure†","year":2019,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Environmental Health Sciences; Institute of Genetics; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Biology; Estrogen receptor; Endocrinology; Epididymis; Estrogen; Internal medicine; Estrogen receptor alpha; Ovary; Diethylstilbestrol; Uterus; Nuclear receptor; Sperm; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004469001,0.0002817096,0.0003768013,0.0000717298,0.0001035212,0.00001202291,0.0002418286,0.0005103787,0.00003228802],"category_scores_gemma":[0.0008196031,0.0002575031,0.0001290022,0.0001648102,0.0001919202,0.00001599913,0.0001882441,0.0002617217,0.00006586569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004414042,"about_ca_system_score_gemma":0.0000870934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002580036,"about_ca_topic_score_gemma":0.000004092594,"domain_scores_codex":[0.9973354,0.0003077554,0.000456417,0.001468239,0.0001203417,0.0003118136],"domain_scores_gemma":[0.9984413,0.00003842735,0.0005249691,0.0007494502,0.0001937128,0.0000521308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006223613,0.00007172852,0.06768007,0.00001512949,0.0002780472,0.000002377782,0.0001952508,0.00003901498,0.9235554,0.000009976066,0.0001277627,0.007402858],"study_design_scores_gemma":[0.0007591523,0.0004309672,0.009984908,0.00004983676,0.00003321551,0.0000273319,0.0006779756,0.000005449293,0.9833766,0.00008458234,0.004283535,0.0002864113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885464,0.009182639,0.00006324438,0.0002055695,0.0009558283,0.0007254111,0.0001142601,0.00008122883,0.0001254248],"genre_scores_gemma":[0.9823156,0.0004405743,0.01482393,0.0000165923,0.0007883248,0.00005234629,0.001331548,0.00003783031,0.0001932279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05982121,"threshold_uncertainty_score":0.9999877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022335829137931,"score_gpt":0.2265821136902495,"score_spread":0.2163587553988702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}