{"id":"W2956018477","doi":"10.1093/biolre/ioz090","title":"Mice lacking membrane estrogen receptor 1 are protected from reproductive pathologies resulting from developmental estrogen exposure†","year":2019,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Environmental Health Sciences; Institute of Genetics; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Biology; Estrogen receptor; Endocrinology; Epididymis; Estrogen; Internal medicine; Estrogen receptor alpha; Ovary; Diethylstilbestrol; Uterus; Nuclear receptor; Sperm; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004617881,0.001017281,0.0007541307,0.001238953,0.0003754238,0.0006001564,0.0005800016,0.001191749,0.007376445],"category_scores_gemma":[0.0002960641,0.0005760182,0.0005557585,0.0002740227,0.0007534663,0.0006442966,0.0004501025,0.001653425,0.001950249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003122435,"about_ca_system_score_gemma":0.0002557434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003534795,"about_ca_topic_score_gemma":0.0008185312,"domain_scores_codex":[0.9994386,0.00006780646,0.00007170167,0.0001719939,0.0001163545,0.000133497],"domain_scores_gemma":[0.9990018,0.00009401019,0.0004401736,0.00009126651,0.00004800517,0.0003247535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009457507,0.0002669345,0.0007953227,0.00007695761,0.0000189637,0.0004118101,0.0000510356,0.00007579521,0.9932339,0.0004102761,0.0002464916,0.003466786],"study_design_scores_gemma":[0.0005473996,0.005301558,0.04192803,0.0001298436,0.000172925,0.006674234,0.0004107414,0.001734889,0.9186172,0.0007259236,0.02367937,0.00007792068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852092,0.002019011,0.004478082,0.0006279395,0.0001690888,0.000116525,0.00390196,0.0006216181,0.002856467],"genre_scores_gemma":[0.9502601,0.00233571,0.005359152,0.0004259671,0.00009456286,0.0003448692,0.003959652,0.0003772758,0.03684264],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007376445,"threshold_uncertainty_score":0.02467662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022335829137931,"score_gpt":0.2265821136902495,"score_spread":0.2163587553988702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}