{"id":"W2956079787","doi":"10.1096/fba.2019-00011","title":"Podocyte GSK3α is important for autophagy and its loss detrimental for glomerular function","year":2019,"lang":"en","type":"article","venue":"FASEB BioAdvances","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; European Commission; National Institutes of Health; Kidney Research UK; Medical Research Council; European Federation of Pharmaceutical Industries and Associations; Innovative Medicines Initiative; Horizon 2020 Framework Programme; Juvenile Diabetes Research Foundation International","keywords":"Podocyte; GSK-3; Cell biology; Albuminuria; Diabetic nephropathy; Autophagy; Gene isoform; Biology; Phosphorylation; Cancer research; Chemistry; Endocrinology; Renal function; Kidney; Biochemistry; Proteinuria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001510427,0.0003171255,0.0002503829,0.0002515974,0.0001854252,0.0003866577,0.0001052296,0.0002634444,0.002126105],"category_scores_gemma":[0.000133147,0.0001352141,0.0003996262,0.0001818689,0.0003058186,0.0002126496,0.0001904353,0.0006657512,0.0004264709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002803302,"about_ca_system_score_gemma":0.000278207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003731087,"about_ca_topic_score_gemma":0.0005263,"domain_scores_codex":[0.9998665,0.00002170701,0.00001945719,0.00002568041,0.00003483636,0.00003188349],"domain_scores_gemma":[0.9998399,0.00001091131,0.0000646225,0.00002186636,0.00001523934,0.00004749358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003103467,0.00002450945,0.0009448743,0.0000902946,0.00001821653,0.0001708725,0.00001147368,0.00004900055,0.9960923,0.0002310543,0.0001360463,0.001921016],"study_design_scores_gemma":[0.00007819026,0.0003685123,0.0300438,0.00003984323,0.00007974679,0.002525694,0.00008054328,0.0006908173,0.9568348,0.0005754198,0.00867176,0.00001091252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806604,0.01172374,0.003255007,0.0006294853,0.0002086796,0.00001757653,0.0004870619,0.0001801176,0.002837928],"genre_scores_gemma":[0.9952799,0.001509972,0.0006118834,0.00008318784,0.00001418787,0.000009680546,0.0001943096,0.00001443367,0.002282399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002126105,"threshold_uncertainty_score":0.007112503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01134063829560954,"score_gpt":0.2807160667067661,"score_spread":0.2693754284111565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}