{"id":"W2956178192","doi":"10.1182/blood.2019000258","title":"Early progression after bendamustine-rituximab is associated with high risk of transformation in advanced stage follicular lymphoma","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Princess Margaret Cancer Centre; Spinal Cord Injury BC; University of British Columbia","funders":"","keywords":"Rituximab; Follicular lymphoma; Medicine; Bendamustine; Internal medicine; Oncology; Prednisone; Vincristine; Population; Hazard ratio; Lymphoma; Immunology; Cyclophosphamide; Confidence interval; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006907277,0.0001634895,0.0003650551,0.0006027136,0.0002459152,0.0007110874,0.0002943442,0.0004371169,0.0007716645],"category_scores_gemma":[0.002489913,0.0002300231,0.0003810929,0.0005734925,0.0002968467,0.0003498601,0.0003773042,0.0006329583,0.0001582427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002412698,"about_ca_system_score_gemma":0.0001765831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001078944,"about_ca_topic_score_gemma":0.0008740944,"domain_scores_codex":[0.9994585,0.0001737486,0.0000605555,0.00009066673,0.0001318784,0.00008462762],"domain_scores_gemma":[0.9980732,0.0003756192,0.001008919,0.0001678534,0.0001207842,0.0002535594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004035445,0.00003461633,0.9953294,0.000005784479,0.00003685912,0.000151219,0.00003171763,0.00007765483,0.0007922647,0.00001098419,0.00004450207,0.003081505],"study_design_scores_gemma":[0.00001371827,0.0002129576,0.9983447,0.000002451423,0.00002519484,0.0007669698,0.00004381263,0.0002650806,0.0001642272,0.00003215553,0.000124907,0.00000383039],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999454,0.0002523139,0.00008820519,0.00001902778,0.000001752098,0.000003540969,0.00003751256,0.000004463323,0.0001391033],"genre_scores_gemma":[0.9997774,0.0000533006,0.00003483931,0.00001150372,0.000005634341,0.000001852921,0.00006728119,0.000001305477,0.00004694441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001078944,"threshold_uncertainty_score":0.00365299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004026528704495895,"score_gpt":0.2221321651778771,"score_spread":0.2181056364733812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}