{"id":"W2956178192","doi":"10.1182/blood.2019000258","title":"Early progression after bendamustine-rituximab is associated with high risk of transformation in advanced stage follicular lymphoma","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Princess Margaret Cancer Centre; Spinal Cord Injury BC; University of British Columbia","funders":"","keywords":"Rituximab; Follicular lymphoma; Medicine; Bendamustine; Internal medicine; Oncology; Prednisone; Vincristine; Population; Hazard ratio; Lymphoma; Immunology; Cyclophosphamide; Confidence interval; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009874634,0.0001559965,0.0003675851,0.00009476082,0.00001929755,0.000009283708,0.00003876352,0.00009385648,0.00009142324],"category_scores_gemma":[0.00001771249,0.0001063849,0.00007994582,0.0002153507,0.00001970838,0.0001414087,0.000009805769,0.00004895501,0.00002338715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008341883,"about_ca_system_score_gemma":0.00006667303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002264706,"about_ca_topic_score_gemma":0.00004867399,"domain_scores_codex":[0.9989477,0.00003740174,0.0002725039,0.0002101885,0.0003300146,0.000202123],"domain_scores_gemma":[0.9994416,0.00003569482,0.0001594496,0.0002205523,0.00008072687,0.00006193791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007274052,0.005297277,0.9828992,0.0001073131,0.000295635,0.000127221,0.001092527,0.00000682196,0.0005754546,0.00002762072,0.000003453088,0.00884011],"study_design_scores_gemma":[0.04887938,0.001531834,0.8975983,0.0007214909,0.0004054563,0.000007257758,0.00007315712,0.00004091725,0.05054441,0.0000101319,0.0000744686,0.0001132168],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998136,0.00035607,0.000004209642,0.00009466489,0.00002588217,0.0009278269,0.0001036295,0.00003253323,0.0003191873],"genre_scores_gemma":[0.9990785,0.00007323631,0.0004551309,0.00004863384,0.000009215526,0.0001402266,0.00007626893,0.00001958578,0.00009924079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08530089,"threshold_uncertainty_score":0.4338251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004026528704495895,"score_gpt":0.2221321651778771,"score_spread":0.2181056364733812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}