{"id":"W2956366404","doi":"10.1002/mds.27786","title":"The genetic and clinico‐pathological profile of early‐onset progressive supranuclear palsy","year":2019,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Movement Disorders","funders":"Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology,University College London; NIHR Sheffield Clinical Research Facility; Medical Research Council; University College London; PSP Association; National Institute for Health and Care Research; Medical Research Council Canada; Koning Boudewijnstichting; Multiple System Atrophy Coalition; Multiple System Atrophy Trust; Department of Health and Social Care; Parkinson's UK","keywords":"Progressive supranuclear palsy; Parkinsonism; Pathological; Medicine; Internal medicine; Gait; Parkinson's disease; Pediatrics; Disease; Physical therapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001197674,0.0001303419,0.0002172222,0.00002810533,0.00007814421,0.00001633275,0.00006943033,0.000053483,0.0002530586],"category_scores_gemma":[0.0000264703,0.00007844133,0.00008239344,0.00006630094,0.0001098632,0.00002485217,0.00006494575,0.00007482924,0.00006186291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001572026,"about_ca_system_score_gemma":0.00003123738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002266972,"about_ca_topic_score_gemma":0.000005659356,"domain_scores_codex":[0.9990222,0.00005066038,0.0002185803,0.000254449,0.0002292336,0.000224875],"domain_scores_gemma":[0.9994508,0.00005185461,0.0001042169,0.0002696087,0.0000314534,0.00009208637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005038088,0.0006101793,0.9632425,0.00006688945,0.0001499598,0.00002587656,0.0001627324,9.577724e-7,0.0004133985,0.0003154438,0.0004475829,0.03406065],"study_design_scores_gemma":[0.002476583,0.001892435,0.9881285,0.00004624851,0.00009796976,9.918455e-7,0.0003510375,0.0001074367,0.0003254889,0.004747551,0.001731726,0.0000940064],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957528,0.001437593,0.000008141212,0.000678337,0.00007703864,0.001122565,0.00002991929,0.00002344548,0.000870157],"genre_scores_gemma":[0.997801,0.0005718449,0.0003914033,0.000606299,0.00001063873,0.00009468194,0.00001391924,0.00001573813,0.0004944409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03396664,"threshold_uncertainty_score":0.3198745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01164199892705805,"score_gpt":0.2702253017012906,"score_spread":0.2585833027742325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}