{"id":"W2956472396","doi":"10.1016/j.clcc.2019.07.005","title":"Effect of Body Mass Index on 5-FU-Based Chemotherapy Toxicity and Efficacy Among Patients With Metastatic Colorectal Cancer; A Pooled Analysis of 5 Randomized Trials","year":2019,"lang":"en","type":"article","venue":"Clinical Colorectal Cancer","topic":"Cancer Risks and Factors","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Colorectal cancer; Oncology; Internal medicine; Randomized controlled trial; Body mass index; Chemotherapy; Oxaliplatin; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004027988,0.0003964703,0.005941383,0.0003550947,0.00003478469,0.00001564334,0.0001332683,0.0002201077,0.0007997868],"category_scores_gemma":[0.002294513,0.0002394002,0.001367883,0.0009259739,0.0006545616,0.00005639581,0.00002536604,0.0003971187,0.000001402146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001874926,"about_ca_system_score_gemma":0.0003621907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001593857,"about_ca_topic_score_gemma":0.0006238309,"domain_scores_codex":[0.9950874,0.001532651,0.001746985,0.0006238813,0.0006914092,0.000317631],"domain_scores_gemma":[0.9871716,0.01048927,0.001480858,0.0002917912,0.0003123171,0.0002541769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3740146,0.0005365511,0.6104103,0.0001775699,0.006746723,0.000002126456,0.00004280917,0.00037397,0.0007980542,0.000001800543,0.00001943143,0.00687602],"study_design_scores_gemma":[0.2485154,0.008562264,0.7093771,0.0002819814,0.01196729,1.125087e-7,0.000005848256,0.007273506,0.01380968,0.000002145123,0.000008530977,0.0001962624],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994311,0.0003743089,0.00006272292,0.00006467127,0.0002915304,0.004498051,0.0002926998,0.00003245035,0.00007250293],"genre_scores_gemma":[0.9988595,0.0003450362,0.00004109561,0.000209119,0.00006939864,0.0003458686,0.00006255478,0.00004323339,0.00002417495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1254993,"threshold_uncertainty_score":0.9762458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02343468710941693,"score_gpt":0.3804631684609261,"score_spread":0.3570284813515092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}