{"id":"W2956632142","doi":"10.1200/jco.2019.37.15_suppl.tps7574","title":"ZUMA-12: A phase 2 multicenter study of axicabtagene ciloleucel (axi-cel) as a first-line therapy in patients (pts) with high-risk large B-cell lymphoma (LBCL).","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Medicine; Internal medicine; Rituximab; Oncology; Surgery; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002646993,0.00205164,0.0015038,0.0005247734,0.0004389966,0.001230069,0.00112564,0.001634849,0.006168787],"category_scores_gemma":[0.001134179,0.0008225169,0.001234567,0.0003914814,0.0008501196,0.001056572,0.0004848258,0.003485771,0.001823226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009362623,"about_ca_system_score_gemma":0.001978379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008976921,"about_ca_topic_score_gemma":0.00234704,"domain_scores_codex":[0.9995775,0.0002122186,0.00001356859,0.00007174941,0.00003933594,0.00008570327],"domain_scores_gemma":[0.9992638,0.00009484389,0.0001438835,0.00005500404,0.00005825008,0.0003841372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6364984,0.162339,0.0095222,0.001490802,0.0018055,0.0004799524,0.0005110504,0.003210136,0.05254458,0.0005720727,0.01357855,0.1174479],"study_design_scores_gemma":[0.7028253,0.2776458,0.009545287,0.00005739597,0.0005665492,0.0005249705,0.00008362078,0.001558638,0.002483129,0.0003039976,0.004370607,0.00003464701],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816085,0.003148415,0.00113485,0.001244551,0.0002626349,0.006722753,0.003007959,0.0003392606,0.002531126],"genre_scores_gemma":[0.9638835,0.003247304,0.005252742,0.002666065,0.0003311774,0.0114035,0.006877365,0.000125997,0.006212394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006168787,"threshold_uncertainty_score":0.02063662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06626956772329211,"score_gpt":0.4377999213158548,"score_spread":0.3715303535925626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}