{"id":"W2956685042","doi":"10.1101/703678","title":"PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Diabetes Canada; Vetenskapsrådet; Karolinska Institutet; International Development Research Centre","keywords":"Inflammation; Biology; Cell biology; Apoptosis; Programmed cell death; Signal transduction; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001918721,0.0002500298,0.0002137722,0.0002858396,0.0001162702,0.0002619432,0.0001368619,0.0001553167,0.0005574392],"category_scores_gemma":[0.0001179903,0.0001068689,0.0002001336,0.0001657521,0.0002920692,0.0001381064,0.0001874618,0.0003912728,0.0001954025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002937829,"about_ca_system_score_gemma":0.0001921344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002737577,"about_ca_topic_score_gemma":0.0004266017,"domain_scores_codex":[0.9998925,0.000020583,0.000008198323,0.00002949712,0.00002541642,0.00002380363],"domain_scores_gemma":[0.9998604,0.00000931889,0.00005663532,0.00001717652,0.00003084281,0.00002554227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001869284,0.00001310969,0.001378026,0.00004004523,0.000009094732,0.00004803283,0.00001804658,0.0001617263,0.995706,0.0001112401,0.00004168817,0.002285976],"study_design_scores_gemma":[0.00005819018,0.0006327213,0.04956986,0.00004019515,0.0000725248,0.0005207246,0.0001743881,0.001774369,0.9406369,0.0006576219,0.005851024,0.0000114587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871914,0.002992027,0.007999709,0.0001594887,0.00005400228,0.00004073846,0.0002154579,0.0001115881,0.001235489],"genre_scores_gemma":[0.9933718,0.00118798,0.002853513,0.00006624853,0.00001580234,0.00003067638,0.0002462298,0.00002063736,0.002207064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005574392,"threshold_uncertainty_score":0.002131522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009246575938564663,"score_gpt":0.2195433626682789,"score_spread":0.2102967867297142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}