{"id":"W2957061490","doi":"10.18433/jpps30358","title":"Neuropeptide FF (FLFQPQRF-NH2) and its Fragments Bind to α2δ Subunit of Voltage-Gated Calcium Channels","year":2019,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Gabapentin; Chemistry; Aminobutyric acid; Cooperativity; Protein subunit; IC50; Biophysics; Amino acid; Biochemistry; Receptor; In vitro; Biology; Gene; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001378324,0.0007141842,0.0003113066,0.0001288124,0.0001200457,0.0001959054,0.0002709859,0.0004429672,0.00203368],"category_scores_gemma":[0.0001701814,0.0001265765,0.0004347786,0.0001362199,0.0002269005,0.000203458,0.0002307752,0.0004573081,0.0007617794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003858266,"about_ca_system_score_gemma":0.0001587762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001438451,"about_ca_topic_score_gemma":0.001050785,"domain_scores_codex":[0.9998819,0.00001888534,0.00001065802,0.00003266724,0.00002653461,0.00002936046],"domain_scores_gemma":[0.9998993,0.00001890974,0.00003450872,0.000006433901,0.00001165891,0.00002907326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001695374,0.00001174014,0.0001633839,0.00004871246,0.000006903382,0.00016044,0.000005878705,0.00008718121,0.9983498,0.00002820737,0.00003442142,0.0009338349],"study_design_scores_gemma":[0.0001234927,0.001012523,0.0133277,0.00003143078,0.00003919279,0.0032606,0.00005173992,0.001093907,0.9742643,0.00005490117,0.006723054,0.00001727084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902169,0.002992322,0.003636601,0.0001216501,0.0000491706,0.00006577395,0.0009475627,0.00002904917,0.001941013],"genre_scores_gemma":[0.9844018,0.001546052,0.007572597,0.0003040292,0.00003538392,0.00008060807,0.002687411,0.00002732646,0.003344797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00203368,"threshold_uncertainty_score":0.006803334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1324281275975359,"score_gpt":0.3987765821870188,"score_spread":0.2663484545894829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}