{"id":"W2957215989","doi":"10.1101/707562","title":"P granules protect RNA interference genes from silencing by piRNAs","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; Johns Hopkins University","keywords":"Piwi-interacting RNA; Argonaute; Gene silencing; RNA interference; RasiRNA; RNA-induced silencing complex; Biology; RNA; Trans-acting siRNA; Cell biology; Small RNA; RNA silencing; Germline; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000130644,0.0003257217,0.0001898247,0.0002185648,0.0001937428,0.0004028524,0.0002235956,0.0003064855,0.001663908],"category_scores_gemma":[0.0001882372,0.0001446876,0.0002383344,0.00007717156,0.0002688351,0.0002605615,0.0004893603,0.0005828003,0.0008810859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002472338,"about_ca_system_score_gemma":0.0001897422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004011168,"about_ca_topic_score_gemma":0.0003920119,"domain_scores_codex":[0.9998873,0.000007702901,0.000007255167,0.00003051392,0.00004423743,0.00002297244],"domain_scores_gemma":[0.9998798,0.00001921928,0.00002228834,0.00003699777,0.00001579263,0.00002593445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004782475,0.000005494784,0.0003362003,0.00001688967,0.000003788244,0.000119643,0.000008222872,0.00009749236,0.9972614,0.0004683279,0.0001514533,0.001483246],"study_design_scores_gemma":[0.00001378718,0.00003976147,0.003391111,0.00000390652,0.000006656986,0.0003278886,0.00001099941,0.001321811,0.9892399,0.0004975109,0.005141024,0.000005599418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9684087,0.0008479114,0.02224595,0.0003373434,0.0001270708,0.00003029771,0.0009640274,0.0009776896,0.006061036],"genre_scores_gemma":[0.9840576,0.0002309887,0.006724353,0.00007581788,0.00002546833,0.00002686904,0.001324494,0.0001962469,0.007338275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001663908,"threshold_uncertainty_score":0.005566299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008209811899030665,"score_gpt":0.231856216820275,"score_spread":0.2236464049212443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}