{"id":"W2957449543","doi":"10.3390/ijms20143471","title":"RUNX3 Promotes the Tumorigenic Phenotype in KGN, a Human Granulosa Cell Tumor-Derived Cell Line","year":2019,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; National Institutes of Health; Alberta Innovates; Rita and Alex Hillman Foundation; Alberta Cancer Foundation; Li Ka Shing Foundation; Royal Alexandra Hospital Foundation; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Children's Health Research Institute; Women and Children's Health Research Institute","keywords":"Cancer research; Biology; Cell growth; Stromal cell; Cell culture; Cell cycle; Cyclin E; Transcription factor; Cell biology; Granulosa cell; Cell; Cyclin-dependent kinase; Cyclin; Ovary; Endocrinology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001019546,0.0001504437,0.0001537109,0.0001969451,0.0001237771,0.0001651065,0.00007042303,0.0001376069,0.00125305],"category_scores_gemma":[0.0001177371,0.00008264314,0.0002342921,0.0001617093,0.000180472,0.00007975252,0.0001053698,0.0002726907,0.0003076938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002047418,"about_ca_system_score_gemma":0.0002796902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00197391,"about_ca_topic_score_gemma":0.003120213,"domain_scores_codex":[0.9999337,0.00001038418,0.000006867112,0.00001105605,0.00002626027,0.0000117192],"domain_scores_gemma":[0.999939,0.000014739,0.00001251446,0.00001369802,0.000007094533,0.00001298142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001014657,0.00002665981,0.0007992072,0.00002571592,0.000003416461,0.00011211,0.0000334052,0.00005714784,0.9975265,0.00006322903,0.00007279457,0.001178409],"study_design_scores_gemma":[0.00004360918,0.0004707833,0.02426372,0.000007449325,0.00002670676,0.001283316,0.00008365151,0.001497652,0.9662635,0.00009266375,0.005961791,0.000005074972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964593,0.0008788695,0.0009044826,0.00009019925,0.00001416718,0.00002707403,0.0003567123,0.00006539564,0.001203933],"genre_scores_gemma":[0.9956043,0.0005591444,0.001152538,0.0000401115,0.000004503644,0.00002675337,0.0008399016,0.00002016652,0.001752656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00197391,"threshold_uncertainty_score":0.004191816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431702735409006,"score_gpt":0.2901154824752484,"score_spread":0.2757984551211584,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}