{"id":"W2957562961","doi":"10.1016/j.exer.2019.107728","title":"Ferroportin-mediated iron export from vascular endothelial cells in retina and brain","year":2019,"lang":"en","type":"article","venue":"Experimental Eye Research","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Kidney Research UK; Research to Prevent Blindness; Genome British Columbia; Paul MacKall and Evanina Bell MacKall Trust; National Eye Institute; British Heart Foundation; F. M. Kirby Foundation","keywords":"Retina; Retinal; Ferroportin; Ferritin; Blood–retinal barrier; Biology; Macular degeneration; Pathology; Cell biology; Medicine; Immunology; Hepcidin; Neuroscience; Endocrinology; Biochemistry; Ophthalmology; Inflammation; Diabetic retinopathy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008286196,0.0001662853,0.0003372325,0.0002429538,0.00006003741,0.00003042984,0.0001242673,0.0001319218,0.002526121],"category_scores_gemma":[0.0001660512,0.0001487603,0.00006730462,0.0002487252,0.0002000707,0.00009980666,0.0001709151,0.0004423926,0.0006916776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009312391,"about_ca_system_score_gemma":0.0001203112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001299776,"about_ca_topic_score_gemma":0.00001155371,"domain_scores_codex":[0.9975429,0.0002168122,0.0003017587,0.0005061563,0.0008799904,0.0005524479],"domain_scores_gemma":[0.999098,0.0001782513,0.00003738443,0.0004068834,0.00004139823,0.000238064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004109249,0.0003974354,0.07807041,0.00004670766,0.000008706553,0.0001103928,0.002025806,5.432655e-7,0.9167311,0.0000761367,0.001648718,0.0004730919],"study_design_scores_gemma":[0.01172876,0.0008128977,0.2291882,0.0001146328,0.00001171443,0.000005681475,0.01700751,0.0001578711,0.7126929,0.00007413768,0.02782124,0.000384468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857852,0.003805945,0.000001246903,0.000444649,0.0001638586,0.0008398949,0.000024796,0.00003101027,0.008903399],"genre_scores_gemma":[0.9962103,0.0002542463,0.000189247,0.0002299426,0.000134963,0.00004870811,0.000107463,0.00003968623,0.00278539],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2040382,"threshold_uncertainty_score":0.9983857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02481396349209992,"score_gpt":0.3556990002520137,"score_spread":0.3308850367599138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}