{"id":"W2957751531","doi":"10.1101/699645","title":"Insight into mosquito GnRH-related neuropeptide receptor specificity revealed through analysis of naturally occurring and synthetic analogs of this neuropeptide family","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"University of Cape Town; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science; National Research Foundation","keywords":"Adipokinetic hormone; Asparagine; Aspartic acid; Receptor; Biochemistry; Serine; Biology; Amino acid; Alanine; Ligand (biochemistry); Neuropeptide Y receptor; Peptide; Neuropeptide; G protein-coupled receptor; Chemistry; Stereochemistry; Phosphorylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001137032,0.0002472395,0.0001471916,0.00009586188,0.00005356514,0.0001384194,0.000139037,0.0001262022,0.0007881945],"category_scores_gemma":[0.00007547026,0.00007550554,0.0001723435,0.00007354061,0.0001144312,0.00008967984,0.00007042196,0.000268904,0.0001963322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001697637,"about_ca_system_score_gemma":0.000097959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002745952,"about_ca_topic_score_gemma":0.0003458701,"domain_scores_codex":[0.9999585,0.000009097254,0.000005537162,0.000007505877,0.000009567031,0.000009869968],"domain_scores_gemma":[0.9999539,0.000007622275,0.00001508819,0.000004970904,0.000006108954,0.00001229534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005484616,0.00001132669,0.000110687,0.00001391446,0.000003195677,0.00002731337,0.000002237088,0.00007315343,0.9992971,0.00002700582,0.000005184554,0.0003740585],"study_design_scores_gemma":[0.00002155579,0.0007381967,0.002536299,0.000003980061,0.00002098472,0.0003136197,0.00001725428,0.001017721,0.9938821,0.00002354071,0.001421196,0.000003607862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974293,0.0004329095,0.001408075,0.00002680328,0.00001037225,0.00002203599,0.0001753517,0.00001024256,0.0004849075],"genre_scores_gemma":[0.995989,0.0004582707,0.002582256,0.00003320053,0.000004735884,0.00001470062,0.0003565897,0.000004738256,0.0005565334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007881945,"threshold_uncertainty_score":0.002636731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02327139193022142,"score_gpt":0.2530047160760025,"score_spread":0.2297333241457811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}