{"id":"W2957795115","doi":"10.3389/fimmu.2019.01705","title":"Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated in vitro Model","year":2019,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"European and Developing Countries Clinical Trials Partnership; Medical Research Council; Inyuvesi Yakwazulu-Natali; National Institutes of Health; National Institute of Allergy and Infectious Diseases; National Research Foundation","keywords":"Human immunodeficiency virus (HIV); In vitro; Toll-like receptor; Toll; Receptor; Immunology; Virology; Biology; Medicine; Cell biology; Immune system; Innate immune system; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042483,0.0008178973,0.0008106824,0.0003433056,0.0003177762,0.0007092353,0.0006598586,0.000731258,0.003220267],"category_scores_gemma":[0.0001935615,0.0003596036,0.0005738143,0.0003960255,0.0002024039,0.0002597088,0.0003471277,0.002203943,0.0014106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003648225,"about_ca_system_score_gemma":0.0002967338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007487002,"about_ca_topic_score_gemma":0.0009224609,"domain_scores_codex":[0.9993274,0.0002247787,0.00007054828,0.0001084892,0.0001273037,0.0001414294],"domain_scores_gemma":[0.9997571,0.00008800261,0.00002581738,0.00005575757,0.00003409963,0.00003918391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007636088,0.000525388,0.0002749096,0.0002375805,0.00002082626,0.0002082168,0.0000743992,0.0005978064,0.9949374,0.0002833066,0.0002766518,0.001799783],"study_design_scores_gemma":[0.0001514481,0.004206044,0.002763313,0.00005151303,0.00009328633,0.0005619499,0.00009028205,0.005732687,0.98102,0.0002815811,0.005030112,0.00001776567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9607937,0.007956516,0.01348024,0.0004522854,0.0006037392,0.0004848174,0.003969254,0.0002411579,0.01201835],"genre_scores_gemma":[0.9687553,0.004067267,0.01263912,0.0004413489,0.0001899348,0.0008835117,0.003566081,0.0000467837,0.009410784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003220267,"threshold_uncertainty_score":0.01077282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006745451689554182,"score_gpt":0.2239779253430671,"score_spread":0.2172324736535129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}