{"id":"W2958239779","doi":"10.1634/theoncologist.2019-0263","title":"Adjuvant Trastuzumab Therapy: Can We Balance Efficacy and Safety?","year":2019,"lang":"en","type":"article","venue":"The Oncologist","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; Population Health Research Institute; McMaster University; Impact","funders":"","keywords":"Trastuzumab; Medicine; Cardiotoxicity; Oncology; Adjuvant; Breast cancer; Internal medicine; Randomized controlled trial; Asymptomatic; Clinical trial; Intensive care medicine; Cancer; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01559861,0.00058278,0.002328129,0.000662549,0.0007914493,0.00348823,0.001634604,0.007595489,0.003833851],"category_scores_gemma":[0.05141431,0.0002276243,0.001123889,0.0005599724,0.002844408,0.006474347,0.001366304,0.01268191,0.001168806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002221234,"about_ca_system_score_gemma":0.004689947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001143499,"about_ca_topic_score_gemma":0.003855109,"domain_scores_codex":[0.9927298,0.004124834,0.0009396274,0.000505625,0.001410682,0.0002893697],"domain_scores_gemma":[0.9741777,0.01887157,0.002092012,0.0004711122,0.00316207,0.00122565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003817073,0.0004694012,0.002758268,0.005370583,0.001212726,0.0005114991,0.0004663265,0.001082367,0.002421129,0.04173787,0.280714,0.6594387],"study_design_scores_gemma":[0.00430407,0.002462643,0.004375789,0.02077454,0.002118165,0.0009136781,0.0009736834,0.001683884,0.001571886,0.1272443,0.8333811,0.0001962625],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.002829961,0.1409461,0.001673593,0.8384967,0.01242749,0.00008422874,0.000081618,0.00003133508,0.003428933],"genre_scores_gemma":[0.0580925,0.1936447,0.006749037,0.6440094,0.09257493,0.0003076521,0.0001145457,0.00006822323,0.004439085],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01559861,"threshold_uncertainty_score":0.08249432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02048914700952035,"score_gpt":0.2785177104400517,"score_spread":0.2580285634305313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}